Macquarie University, Sydney Macquarie University ResearchOnline

Showing items 31 - 42 of 42.

Add to Quick Collection   All 42 Results

Sort:
 Add All Items to Quick Collection
Date: 2013
Subject Keyword: Alzheimer's | aging | diagnosis | pupil | screening | vision
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1143755
Description: Introduction: A screening process that could provide early and accurate diagnosis or prognosis for Alzheimer’s disease (AD) would enable earlier intervention, and enable current and future treatments ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/269405
Description: Background: To date evidence of the relationship between cognition and Aβ amyloid during the early stages of Alzheimer's Disease (AD) has been inconsistent. This study aimed to describe the nature and ... More
Reviewed: Reviewed
Date: 2012
Subject Keyword: 110700 Immunology
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/169624
Description: A number of genetic risk factors have been identified for Alzheimer's disease (AD) including genes involved in the inflammatory response (interleukin 1A, [IL-1α (-889)], interleukin 1B (IL-1β [+3953]) ... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1074465
Description: Background: Alcadeinα (Alcα) is a neuronal membrane protein that colocalizes with the Alzheimer's amyloid-β precursor protein (APP). Successive cleavage of APP by β- and γ-secretases generates the agg ... More
Full Text: Full Text
Reviewed: Reviewed
Date: 2012
Subject Keyword: 170100 Psychology
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/201765
Description: Objective: Although the APOE ε4 allele is associated with more rapid decline in memory in healthy older adults, the significance of elevated cerebral β-amyloid (Aβ) load for longitudinal changes in co ... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/174968
Description: The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with m ... More
Reviewed: Reviewed
Date: 2011
Subject Keyword: 170100 Psychology
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/165762
Description: • A decline in cognition greater than expected with ageing and accompanied by subjective cognitive concerns or functional changes may be indicative of a dementing disorder. • The capacity to correctly ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1099582
Description: 2 page(s)
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1098770
Description: A strong link is indicated between cardiovascular disease (CVD) and risk for developing Alzheimer's disease (AD), which may be exacerbated by the major AD genetic risk factor apolipoprotein Eε4 (APOEε ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1098965
Description: Olfactory dysfunction has been reported in clinical and preclinical phases of Alzheimer's disease. Subjective memory complaints have been proposed as a potential early indicator for increased risk of ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/84718
Description: The Australian Imaging, Biomarkers and Lifestyle (AIBL) flagship study of aging aimed to recruit 1000 individuals aged over 60 to assist with prospective research into Alzheimer's disease (AD). This p ... More
Full Text: Full Text
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1098855
Description: Apolipoprotein E epsilon4 (APOE-ε4) is a major genetic risk factor for Alzheimer's disease. In this study, we addressed the question of whether possession of the APOE-ε4 allele results in adverse effe ... More
Reviewed: Reviewed