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Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1220054
Description: Mutations in the optineurin gene (OPTN) have been identified in a small proportion (<1%) of sporadic and familial ALS cases, and the exact role of optineurin in the pathogenesis of ALS remains unclear ... More
Reviewed: Reviewed
Date: 2017
Subject Keyword: SNP | mutation | homology modelling | caveolin
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1220442
Description: The caveolin (Cav) family of proteins comprises key constituents of caveolar structures in cell membranes, which are involved in receptor-independent endocytosis and cellular signalling pathways. Thre ... More
Reviewed: Reviewed
Date: 2015
Subject Keyword: BRAF | case | cutis | diffuse | melanosis | mutation | therapy | treatment | positive
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1063387
Description: Diffuse melanosis cutis (DMC) is a rare presentation of metastatic melanoma associated with a particularly guarded prognosis. We report a case of a 35-year-old man with BRAFV600E metastatic melanoma t ... More
Reviewed: Reviewed
Authors: Qin, Huayu
Date: 2015
Language: eng
Resource Type: Thesis MPhil
Identifier: http://hdl.handle.net/1959.14/1069726
Description: "This thesis is presented as a partial fulfillment to the requirements for the degree of Master of Philosophy, Department of Chemistry and Biomolecular Sciences".
Full Text: Full Text
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1063562
Description: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that arises from the progressive degeneration of the motor neurons. Recently, mutations in the matrin 3 (MATR3) gene were descr ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1048674
Description: Missense and frameshift mutations in TRAF family member-associated NF-kappa-B activator (TANK)-binding kinase 1 (TBK1) have been reported in European sporadic and familial amyotrophic lateral sclerosi ... More
Reviewed: Reviewed
Date: 2006
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/8140
Description: Scorpion toxins are important physiological probes for characterizing ion channels. Molecular databases have limited functional annotation of scorpion toxins. Their function can be inferred by searchi ... More
Reviewed: Reviewed
Date: 2006
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/8217
Description: Scorpion toxins are important experimental tools for characterization of vast array of ion channels and serve as scaffolds for drug design. General public database entries contain limited annotation w ... More
Reviewed: Reviewed
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