Macquarie University, Sydney Macquarie University ResearchOnline

Showing items 1 - 15 of 15.

Add to Quick Collection   All 15 Results

  • First
  • Previous
  • 1
  • Next
  • Last
Sort:
 Add All Items to Quick Collection
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/263068
Description: We report progress assembling the parts list for chromosome 17 and illustrate the various processes that we have developed to integrate available data from diverse genomic and proteomic knowledge base ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/263030
Description: In this study we selected three breast cancer cell lines (SKBR3, SUM149 and SUM190) with different oncogene expression levels involved in ERBB2 and EGFR signaling pathways as a model system for the ev ... More
Reviewed: Reviewed
Date: 2010
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/216889
Description: TNK-tPA products from the innovator and follow-on manufacturers were characterized and compared. All tryptic peptides including N-terminal, C-terminal, and mutated peptides as well as the disulfide-li ... More
Reviewed: Reviewed
Date: 2010
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/216060
Description: Recombinant tissue plasminogen (rt-PA) with 35 cysteine residues has been completely assigned by mapping the 17 disulfide linkages and the unpaired cysteine. The result is consistent with the predicti ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117673
Description: Three different analysis platforms using LC-MS were successfully developed for pharmacokinetic (PK) studies of an antibody drug in serum. These analysis platforms can be selectively used for different ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 100400 Medical Biotechnology
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117584
Description: We have performed a detailed characterization of recombinant human growth hormone that included the identification of the entire sequence with disulfide linkages as well as subtle modifications by a s ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117695
Description: In the biotechnology industry, the generation of incorrectly folded recombinant proteins, either from an E.coli expression system or from an overexpressed CHO cell line (disulfide scrambling), is ofte ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/148102
Description: In this study, we report a combined proteomic and peptidomic analysis of human plasma from patients with rheumatoid arthritis (RA) and controls. We used molecular weight cut-off filters (MWCO: 10 kDa) ... More
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117700
Description: The purpose of this study was to identify the protein profile of the mouse brain microvascular endothelium in situ. This involved coupling of a double-label, immuno-laser capture microdissection (LCM) ... More
Reviewed: Reviewed
Date: 2007
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117623
Description: The purpose of this discovery phase study was to identify candidate protein biomarkers for high-grade dysplastic cervical cells using mass spectrometry. Laser Capture Microdissection (LCM) was utilize ... More
Reviewed: Reviewed
Date: 2006
Subject Keyword: 110300 Clinical Sciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117651
Description: In this publication, we will describe the combination of lectin affinity chromatography with nano high performance liquid chromatography (HPLC) coupled to a linear ion trap Fourier transform mass spec ... More
Reviewed: Reviewed
Date: 2006
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117613
Description: Glycation of interferon-beta-1b and human serum albumin was identified in a lyophilized glucose formulation by a sensitive LC-MS approach. The extent of glycation was measured by a label-free quantita ... More
Reviewed: Reviewed
Date: 2006
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117593
Description: In this paper, we describe the combination of lectin chromatography with capillary LC coupled to a linear ion trap-Fourier transform mass spectrometer (LTQ/FTMS) to enrich and characterize overexpress ... More
Reviewed: Reviewed
  • First
  • Previous
  • 1
  • Next
  • Last