Macquarie University, Sydney Macquarie University ResearchOnline

Showing items 1 - 14 of 14.

Add to Quick Collection   All 14 Results

  • First
  • Previous
  • 1
  • Next
  • Last
Sort:
 Add All Items to Quick Collection
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1048538
Description: Background: The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic fact ... More
Reviewed: Reviewed
Authors: Akbani, Rehan | Akdemir, Kadir C | Baboud, Julien | Gomez-Fernandez, Carmen | Gribbin, Thomas | Grimsby, Jonna | Gross, Benjamin | Guin, Ranabir | Gutschner, Tony | Hadjipanayis, Angela | Halaban, Ruth | Hanf, Benjamin | Haussler, David | Balasundaram, Miruna | Haydu, Lauren E | Hayes, D. Neil | Hayward, Nicholas K | Heiman, David I | Herbert, Lynn | Herman, James G | Hersey, Peter | Hoadley, Katherine A | Hodis, Eran | Holt, Robert A | Balu, Saianand | Hoon, Dave S. B | Hoppough, Susan | Hoyle, Alan P | Huang, Franklin W | Huang, Mei | Huang, Sharon | Hutter, Carolyn M | Ibbs, Matthew | Iype, Lisa | Jacobsen, Anders | Barnabas, Nandita | Jakrot, Valerie | Janning, Alyssa | Jeck, William R | Jefferys, Stuart R | Jensen, Mark A | Jones, Corbin D | Jones, Steven J. M | Ju, Zhenlin | Kakavand, Hojabr | Kang, Hyojin | Bartlett, John | Kefford, Richard F | Khuri, Fadio R | Kim, Jaegil | Kirkwood, John M | Klode, Joachim | Korkut, Anil | Korski, Konstanty | Krauthammer, Michael | Kucherlapati, Raju | Kwong, Lawrence N | Bartlett, Pam | Kycler, Witold | Ladanyi, Marc | Lai, Phillip H | Laird, Peter W | Lander, Eric | Lawrence, Michael S | Lazar, Alexander J | Łaźniak, Radoslaw | Lee, Darlene | Lee, Jeffrey E | Bastian, Boris C | Lee, Junehawk | Lee, Kenneth | Lee, Semin | Lee, William | Leporowska, Ewa | Leraas, Kristen M | Li, Haiyan I | Lichtenberg, Tara M | Lichtenstein, Lee | Lin, Pei | Baylin, Stephen B | Ling, Shiyun | Liu, Jia | Liu, Ouida | Liu, Wenbin | Long, Georgina V | Lu, Yiling | Ma, Singer | Ma, Yussanne | Mackiewicz, Andrzej | Mahadeshwar, Harshad S | Behera, Madhusmita | Malke, Jared | Mallery, David | Manikhas, Georgy M | Mann, Graham J | Marra, Marco A | Matejka, Brenna | Mayo, Michael | Mehrabi, Sousan | Meng, Shaowu | Meyerson, Matthew | Belyaev, Dmitry | Mieczkowski, Piotr A | Miller, John P | Miller, Martin L | Mills, Gordon B | Moiseenko, Fedor | Moore, Richard A | Morris, Scott | Morrison, Carl | Morton, Donald L | Moschos, Stergios | Aksoy, B. Arman | Benz, Christopher | Mose, Lisle E | Muller, Florian L | Mungall, Andrew J | Murawa, Dawid | Murawa, Pawel | Murray, Bradley A | Nezi, Luigi | Ng, Sam | Nicholson, Dana | Noble, Michael S | Bernard, Brady | Osunkoya, Adeboye | Owonikoko, Taofeek K | Ozenberger, Bradley A | Pagani, Elena | Paklina, Oxana V | Pantazi, Angeliki | Parfenov, Michael | Parfitt, Jeremy | Park, Peter J | Park, Woong-Yang | Beroukhim, Rameen | Parker, Joel S | Passarelli, Francesca | Penny, Robert | Perou, Charles M | Pihl, Todd D | Potapova, Olga | Prieto, Victor G | Protopopov, Alexei | Quinn, Michael J | Radenbaugh, Amie | Bir, Natalie | Rai, Kunal | Ramalingam, Suresh S | Raman, Ayush T | Ramirez, Nilsa C | Ramirez, Ricardo | Rao, Uma | Rathmell, W. Kimryn | Ren, Xiaojia | Reynolds, Sheila M | Roach, Jeffrey | Black, Aaron D | Robertson, A. Gordon | Ross, Merrick I | Roszik, Jason | Russo, Giandomenico | Saksena, Gordon | Saller, Charles | Samuels, Yardena | Sander, Chris | Sander, Cindy | Sandusky, George | Bodenheimer, Tom | Santoso, Netty | Saul, Melissa | Saw, Robyn P. M | Schadendorf, Dirk | Schein, Jacqueline E | Schultz, Nikolaus | Schumacher, Steven E | Schwallier, Charles | Scolyer, Richard A | Seidman, Jonathan | Boice, Lori | Sekhar, Pedamallu Chandra | Sekhon, Harmanjatinder S | Senbabaoglu, Yasin | Seth, Sahil | Shannon, Kerwin F | Sharpe, Samantha | Sharpless, Norman E | Shaw, Kenna R. Mills | Shelton, Candace | Shelton, Troy | Boland, Genevieve M | Shen, Ronglai | Sheth, Margi | Shi, Yan | Shiau, Carolyn J | Shmulevich, Ilya | Sica, Gabriel L | Simons, Janae V | Sinha, Rileen | Sipahimalani, Payal | Sofia, Heidi J | Bono, Riccardo | Soloway, Matthew G | Song, Xingzhi | Sougnez, Carrie | Spillane, Andrew J | Spychala, Arkadiusz | Stretch, Jonathan R | Stuart, Joshua | Suchorska, Wiktoria M | Sucker, Antje | Sumer, S. Onur | Bootwalla, Moiz S | Sun, Yichao | Synott, Maria | Tabak, Barbara | Tabler, Teresa R | Tam, Angela | Tan, Donghui | Tang, Jiabin | Tarnuzzer, Roy | Tarvin, Katherine | Tatka, Honorata | Albert, Monique | Bosenberg, Marcus | Taylor, Barry S | Teresiak, Marek | Thiessen, Nina | Thompson, John F | Thorne, Leigh | Thorsson, Vesteinn | Trent, Jeffrey M | Triche Jr., Timothy J | Tsai, Kenneth Y | Tsou, Peiling | Bowen, Jay | Van Den Berg, David J | Van Allen, Eliezer M | Veluvolu, Umadevi | Verhaak, Roeland G | Voet, Douglas | Voronina, Olga | Walter, Vonn | Walton, Jessica S | Wan, Yunhu | Wang, Yuling | Bowlby, Reanne | Wang, Zhining | Waring, Scot | Watson, Ian R | Weinhold, Nils | Weinstein, John N | Weisenberger, Daniel J | White, Peter | Wilkerson, Matthew D | Wilmott, James S | Wise, Lisa | Bristow, Christopher A | Wiznerowicz, Maciej | Woodman, Scott E | Wu, Chang-Jiun | Wu, Chia-Chin | Wu, Junyuan | Wu, Ye | Xi, Ruibin | Xu, Andrew Wei | Yang, Da | Yang, Liming | Brockway-Lunardi, Laura | Yang, Lixing | Zack, Travis I | Zenklusen, Jean C | Zhang, Hailei | Zhang, Jianhua | Zhang, Wei | Zhao, Xiaobei | Zhu, Jingchun | Zhu, Kelsey | Zimmer, Lisa | Brooks, Denise | Zmuda, Erik | Zou, Lihua | Brzezinski, Jakub | Bshara, Wiam | Buda, Elizabeth | Burns, William R | Ally, Adrian | Butterfield, Yaron S. N | Button, Michael | Calderone, Tiffany | Cappellini, Giancarlo Antonini | Carter, Candace | Carter, Scott L | Cherney, Lynn | Cherniack, Andrew D | Chevalier, Aaron | Chin, Lynda | Amin, Samirkumar B | Cho, Juok | Cho, Raymond J | Choi, Yoon-La | Chu, Andy | Chudamani, Sudha | Cibulskis, Kristian | Ciriello, Giovanni | Clarke, Amanda | Coons, Stephen | Cope, Leslie | Arachchi, Harindra | Crain, Daniel | Curley, Erin | Danilova, Ludmila | D'Atri, Stefania | Davidsen, Tanja | Davies, Michael A | Delman, Keith A | Demchok, John A | Deng, Qixia A | Deribe, Yonathan Lissanu | Arora, Arshi | Dhalla, Noreen | Dhir, Rajiv | DiCara, Daniel | Dinikin, Michael | Dubina, Michael | Ebrom, J. Stephen | Egea, Sophie | Eley, Greg | Engel, Jay | Eschbacher, Jennifer M | Auman, J. Todd | Fedosenko, Konstantin V | Felau, Ina | Fennell, Timothy | Ferguson, Martin L | Fisher, Sheila | Flaherty, Keith T | Frazer, Scott | Frick, Jessica | Fulidou, Victoria | Gabriel, Stacey B | Ayala, Brenda | Gao, Jianjiong | Gardner, Johanna | Garraway, Levi A | Gastier-Foster, Julie M | Gaudioso, Carmelo | Gehlenborg, Nils | Genovese, Gianicola | Gerken, Mark | Gershenwald, Jeffrey E | Getz, Gad
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1062489
Description: We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients. We establish a framew ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: conference paper abstract
Identifier: http://hdl.handle.net/1959.14/1060785
Description: Purpose: To evaluate the association between the immunoreactivity of the immune inhibitory ligand PD-L1 with tumour infiltrating lymphocytes (TILs) and known mechanisms of MAPK inhibitor (MAPKi) resis ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1057803
Description: Purpose: To evaluate the expression of tumor PD-L1 and changes in tumor-infiltrating lymphocyte (TIL) populations in patients with metastatic melanoma treated with targeted MAPK inhibitors. Experiment ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1059727
Description: This study evaluated the expression of PD-L1 in immunotherapy-naïve metastatic melanoma patients to determine longitudinal intrapatient concordance and correlate PD-L1 status with clinicopathologic ch ... More
Reviewed: Reviewed
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/341690
Description: There is concern that BRAF mutant naevus cells admixed with melanoma cells could cause false positive mutation tests in BRAF wild-type melanomas. We sought to assess the frequency of BRAFV600E mutatio ... More
Reviewed: Reviewed
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/341707
Description: The purpose of this study is to profile the changes in the serum levels of a range of chemokines, cytokines, and growth and angiogenic factors in MAPK inhibitor-treated metastatic melanoma patients an ... More
Reviewed: Reviewed
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/340728
Description: Concern regarding the presence of intertumoral heterogeneity of BRAF mutation status in patients with metastatic melanoma has led to uncertainty surrounding which specimens should preferentially under ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294242
Description: Prediction of outcome for melanoma patients with surgically resected macroscopic nodal metastases is very imprecise. We performed a comprehensive clinico-pathologic assessment of fresh-frozen macrosco ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294203
Description: Selective BRAF inhibitors (BRAFi) are a standard of care for the treatment of BRAFV600-mutant metastatic melanoma. We analyzed a unique set of serial triplicate human metastatic melanoma tumor biopsie ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294119
Description: This study investigated the sensitivity and specificity of immunohistochemical (IHC) analysis using an anti-BRAF antibody to detect the presence of the BRAF V600E mutation in patients with metastatic ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/299864
Description: Inositol polyphosphate 5-phosphatases can terminate downstream signalling of phosphatidylinositol-3 kinase; however, their biological role in the pathogenesis of cancer is controversial. Here we repor ... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294768
Description: Targeted therapies are increasingly being used to treat a variety of cancers. Their efficacy depends upon the accurate detection and targeting of a specific mutation or aberration in the tumor. All ca ... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294754
Description: Purpose: To evaluate the effects of treatment with the potent mutant BRAF inhibitors GSK2118436 or vemurafenib (PLX4720) on immune responses to metastatic melanoma in tissues taken before and after tr ... More
Reviewed: Reviewed
  • First
  • Previous
  • 1
  • Next
  • Last