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Date: 2017
Subject Keyword: SNP | mutation | homology modelling | caveolin
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1220442
Description: The caveolin (Cav) family of proteins comprises key constituents of caveolar structures in cell membranes, which are involved in receptor-independent endocytosis and cellular signalling pathways. Thre ... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1074386
Description: The APP-PS1ΔE9 mouse model of Alzheimer's disease (AD) exhibits age dependent amyloid β (Aβ) plaque formation in their central nervous system due to high expression of mutated human APP and PSEN1 tran ... More
Reviewed: Reviewed
Date: 2016
Subject Keyword: TrkB | Cyclotraxin B | GSK3β | docking
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1184602
Description: TrkB is a high affinity receptor for the brain derived neurotrophic factor (BDNF) and its phosphorylation stimulates activation of several intracellular signalling pathways linked to cellular growth, ... More
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1196456
Description: Accumulation of amyloid β (Aβ) and its aggregates in the ageing central nervous system is regarded synonymous to Alzheimer’s disease (AD) pathology. Despite unquestionable advances in mechanistic and ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: conference paper abstract
Identifier: http://hdl.handle.net/1959.14/1062364
Description: Purpose: The serine protease inhibitor, neuroserpin, is predominantly expressed in neural tissues and is well expressed in the vitreous and retina. There is evidence of involvement of proteases in mat ... More
Date: 2015
Language: eng
Resource Type: conference paper abstract
Identifier: http://hdl.handle.net/1959.14/1048711
Description: Glucoprivation or hypoglycaemia evokes a complex array of counterregulatory responses which include autonomic, neuroendocrine and behavioural changes in order to maintain blood glucose levels. Catecho ... More
Date: 2014
Language: eng
Resource Type: Thesis MRes
Identifier: http://hdl.handle.net/1959.14/1257119
Description: Theoretical thesis.
Full Text: Full Text
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