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Authors: Lee, S. Hong | Harold, Denise | Lechner-Scott, Jeannette | Rujescu, Dan | Goate, Alison | Cruchaga, Carlos | Nowotny, Petra | Morris, | Mayo, Kevin | Livingston, Gill | Bass, Nicholas J | Gurling, Hugh | McQuillin, Andrew | Moscato, Pablo | Gwilliam, Rhian | Deloukas, Panagiotis | Nöthen, Markus M | Holmans, Peter | O'Donovan, Michael | Owen, Michael J | Booth, David R | Stewart, Graeme J | Heard, Robert N | Mason, Deborah | Griffiths, Lyn | Broadley, Simon | Brown, Matthew A | Slee, Mark | Nyholt, Dale R | Foote, Simon J | Stankovich, Jim | Taylor, Bruce V | Wiley, James | Bahlo, Melanie | Perreau, Victoria | Field, Judith | Butzkueven, Helmut | Kilpatrick, Trevor J | Rubio, Justin | Goddard, Michael E | Marriott, Mark | Carroll, William M | Kermode, Allan G | Anderson, Carl A | Gordon, Scott D | Guo, Qun | Henders, Anjali K | Lambert, Ann | Kraft, Peter | Kennedy, Stephen H | Zondervan, Krina T | Macgregor, Stuart | Martin, Nicholas G | Missmer, Stacey A | Morris, Andrew P | Painter, Jodie N | Roseman, Fenella | Treloar, Susan A | Wallace, Leanne | Sims, Rebecca | Gerrish, Amy | Williams, Julie | Chapman, Jade | Moskvina, Valentina | Abraham, Richard | Hollingworth, Paul | Hamshere, Marian | Pahwa, Jaspreet Singh | Dowzell, Kimberley | Williams, Amy | Jones, Nicola | Thomas, Charlene | Montgomery, Grant W | Stretton, Alexandra | Morgan, Angharad | Lovestone, Simon | Powell, John | Proitsi, Petroula | Lupton, Michelle K | Brayne, Carol | Rubinsztein, David C | Gill, Michael | Lawlor, Brian | Wray, Naomi R | Lynch, Aoibhinn | Morgan, Kevin | Brown, Kristelle | Passmore, Peter | Craig, David | McGuinness, Bernadette | Todd, Stephen | Holmes, Clive | Mann, David | Smith, A. David | Visscher, Peter M | Love, Seth | Kehoe, Patrick G | Hardy, John | Mead, Simon | Fox, Nick | Rossor, Martin | Collinge, John | Maier, Wolfgang | Jessen, Frank | Heun, Reiner | Scott, Rodney J | Kölsch, Heike | Schürmann, Britta | van den Bussche, Hendrik | Heuser, Isabella | Kornhuber, Johannes | Wiltfang, Jens | Martin, Dichgans | Frölich, Lutz | Hampel, Harald | Hüll, Michael
Date: 2013
Subject Keyword: 110900 Neurosciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/288993
Description: Common diseases such as endometriosis (ED), Alzheimer's disease (AD) and multiple sclerosis (MS) account for a significant proportion of the health care burden in many countries. Genome-wide associati ... More
Reviewed: Reviewed
Date: 2013
Subject Keyword: 110300 Clinical Sciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/288671
Description: Genome-wide association studies (GWAS) have identified around 60 common variants associated with multiple sclerosis (MS), but these loci only explain a fraction of the heritability of MS. Some missing ... More
Full Text: Full Text
Reviewed: Reviewed
Date: 2012
Subject Keyword: 110300 Clinical Sciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/200227
Description: Background: One primary goal of transcriptomic studies is identifying gene expression patterns correlating with disease progression. This is usually achieved by considering transcripts that independen ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.14/156322
Description: Novel analytical techniques have dramatically enhanced our understanding of many application domains including biological networks inferred from gene expression studies. However, there are clear compu ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/295524
Description: Background: Illumina's Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw allele A and allele B inte ... More
Full Text: Full Text
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/305446
Description: Objective: To perform a 1-stage meta-analysis of genome-wide association studies (GWAS) of multiple sclerosis (MS) susceptibility and to explore functional consequences of new susceptibility loci. Met ... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/140996
Description: Therapies consisting of a combination of agents are an attractive proposition, especially in the context of diseases such as cancer, which can manifest with a variety of tumor types in a single case. ... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/140999
Description: Clustering, particularly hierarchical clustering, is an important method for understanding and analysing data across a wide variety of knowledge domains with notable utility in systems where the data ... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294016
Description: It is well established that Multiple Sclerosis (MS) is an immune mediated disease. Little is known about what drives the differential control of the immune system in MS patients compared to unaffected ... More
Full Text: Full Text
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294130
Description: As of June 2009, 361 genome-wide association studies (GWAS) had been referenced by the HuGE database. GWAS require DNA from many thousands of individuals, relying on suitable DNA collections. We recen ... More
Reviewed: Reviewed
Date: 2010
Subject Keyword: 110900 Neurosciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294221
Description: Multiple sclerosis (MS) is an autoimmune disease with a genetic component, caused at least in part by aberrant lymphocyte activity. The whole blood mRNA transcriptome was measured for 99 untreated MS ... More
Reviewed: Reviewed
Date: 2005
Subject Keyword: 080300 Computer Software
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.14/138077
Description: 9 page(s)
Reviewed: Reviewed
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