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Date: 2015
Subject Keyword: aging | sirtuins | p53 | brain | longevity
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/355709
Description: Although there are seven mammalian sirtuins (SIRT1-7), little is known about their expression in the aging brain. To characterize the change(s) in mRNA and protein expression of SIRT1-7 and their asso ... More
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Reviewed: Reviewed
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1018219
Description: Over the last decade, the importance of NAD⁺ has expanded beyond its role as an essential cofactor for energy metabolism. NAD⁺ has emerged as a major signalling molecule that serves as the sole substr ... More
Reviewed: Reviewed
Date: 2011
Subject Keyword: 110900 Neurosciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/223163
Description: The cofactor nicotinamide adenine dinucleotide (NAD⁺) has emerged as a key regulator of metabolism, stress resistance and longevity. Apart from its role as an important redox carrier, NAD⁺ also serves ... More
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Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/223103
Description: The kynurenine pathway of tryptophan catabolism plays an important role in several biological systems affected by aging. We quantified tryptophan and its metabolites kynurenine (KYN), kynurenine acid ... More
Reviewed: Reviewed
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