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Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/341896
Description: Integrin αvβ6 is an epithelially-restricted heterodimeric transmembrane glycoprotein, known to interact with the urokinase plasminogen activating receptor (uPAR), playing a critical role in cancer pro ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: collection
Identifier: mq:29603
Description: The goal of the project was to develop a dataset to understand the physicochemical basis for the selection of certain specific peptide epitopes by major histocompatibility complex (MHC) alleles and th ... More
Date: 2012
Subject Keyword: 110700 Immunology
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/186675
Description: Background HLA-DQ alleles are involved in the pathogenesis of hypersensitivity reactions, with HLA-DQ8 associated with several human autoimmune disorders. Limited success has been achieved using seque ... More
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Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.14/165905
Description: Background: Lysosomal β-D-mannosidase is a glycosyl hydrolase that breaks down the glycosidic bonds at the non-reducing end of N-linked glycoproteins. Hence, it is a crucial enzyme in polysaccharide d ... More
Reviewed: Reviewed
Date: 2011
Subject Keyword: 060400 Genetics
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/143769
Description: Sequence-structure-function information is critical in understanding the mechanism of pMHC and TR/pMHC binding and recognition. A database for sequence-structure-function information on pMHC and TR/pM ... More
Reviewed: Reviewed
Date: 2011
Subject Keyword: 060400 Genetics
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/136234
Description: Understanding the basis of the binding of a T cell receptor (TR) to the peptide-MHC (pMHC) complex is essential due to the vital role it plays in adaptive immune response. We describe the use of compu ... More
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Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/166608
Description: Background: Identification of antigenic peptide epitopes is an essential prerequisite in T cell-based molecular vaccine design. Computational (sequence-based and structure-based) methods are inexpensi ... More
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Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: book chapter
Identifier: http://hdl.handle.net/1959.14/93265
Description: Adaptive immune responses are governed by major histocompatibility complexes (MHC) binding to specific short antigenic peptides and then this peptide bound major histocompatibility complex (pMHC) bein ... More
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