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Authors: Bell, Alexander W | Deutsch, Eric W | Meredith, Gavin | Vizca�no, Juan Antonio | Sheffield, Peter | Gray, Phillip | Hajivandi, Mahbod | Pope, Marshall | Predki, Paul | Kullolli, Majlinda | Hincapie, Maria | Hancock, William Stephen | Jia, Wei | Au, Catherine E | Song, Lina | Li, Lei | Wei, Junying | Yang, Bing | Wang, Jinglan | Ying, Wantao | Zhang, Yangjun | Cai, Yun | Qian, Xiaohong | He, Fuchu | Kearney, Robert E | Meyer, Helmut | Stephan, Christian | Eisenacher, Martin | Marcus, Katrin | Langenfeld, Elmar | May, Caroline | Carr, Steven A | Ahmad, Rushdy | Zhu, Wenhong | Smith, Jeffrey W | Beavis, Ron | Hanash, Samir M | Struthers, Jason J | Wang, Hong | Zhang, Qing | An, Yanming | Goldman, Radoslav | Carlsohn, Elisabet | van der Post, Sjoerd | Hung, Kenneth E | Sarracino, David A | Sechi, Salvatore | Parker, Kenneth | Krastins, Bryan | Kucherlapati, Raju | Bourassa, Sylvie | Poirier, Guy G | Kapp, Eugene A | Patsiouras, Heather | Moritz, Robert L | Simpson, Richard J | Houle, Benoit | Nilsson, Thomas | LaBoissiere, Sylvie | Metalnikov, Pavel | Nguyen, Vivian | Pawson, Tony | Wong, Catherine C. L | Cociorva, Daniel | Yates, J.R | Lopez-Campistrous, Ana | Semchuk, Paul | Wang, Yueju | Bergeron, John J. M | Ping, Peipei | Elia, Giuliano | Dunn, Michael J | Wynne, Kieran | Walker, Angela K | Strahler, John R | Andrews, Philip | Hood, Brian L | Bigbee, William L | Conrads, Thomas P | Beardslee, Thomas A | Smith, Derek | Borchers, Christoph H | Lajoie, Gilles A | Bendall, Sean C | Speicher, Kaye D | Speicher, David W | Fujimoto, Masanori | Nakamura, Kazuyuki | Paik, Young-Ki | Cho, Sang Yun | Chappell, Thomas | Kwon, Min-Seok | Lee, Hyoung-Joo | Jeong, Seul-Ki | Chung, An Sung | Miller, Christine A | Grimm, Rudolf | Williams, Katy | Dorschel, Craig | Falkner, Jayson A | Martens, Lennart
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1186504
Description: We performed a test sample study to try to identify errors leading to irreproducibility, including incompleteness of peptide sampling, in liquid chromatography-mass spectrometry-based proteomics. We d ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117708
Description: Liquid Chromatography Mass Spectrometry (LC-MS) based proteomics is an important tool in detecting changes in peptide/protein abundances in samples potentially leading to the discovery of disease biom ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117673
Description: Three different analysis platforms using LC-MS were successfully developed for pharmacokinetic (PK) studies of an antibody drug in serum. These analysis platforms can be selectively used for different ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 100400 Medical Biotechnology
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117584
Description: We have performed a detailed characterization of recombinant human growth hormone that included the identification of the entire sequence with disulfide linkages as well as subtle modifications by a s ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117695
Description: In the biotechnology industry, the generation of incorrectly folded recombinant proteins, either from an E.coli expression system or from an overexpressed CHO cell line (disulfide scrambling), is ofte ... More
Reviewed: Reviewed
Date: 2009
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117713
Description: The productivity of mammalian cell culture expression systems is critically important to the production of biopharmaceuticals. In this study, a high-producing Chinese hamster ovary cell culture which ... More
Reviewed: Reviewed
Date: 2008
Subject Keyword: 030100 Analytical Chemistry
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1127894
Description: In this study, we report a plasma proteomic analysis of a mouse MCF7 xenograft, using a novel platform named M-LAC (multilectin affinity chromatography), in an attempt to identify putative serum bioma ... More
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117688
Description: Plasma is an important biological material for biomarker discovery. However, the wide dynamic range in protein concentration remains a major challenge. In this paper, we introduce the development of a ... More
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117700
Description: The purpose of this study was to identify the protein profile of the mouse brain microvascular endothelium in situ. This involved coupling of a double-label, immuno-laser capture microdissection (LCM) ... More
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117619
Description: Endothelial cells are subjected to mechanical forces in the form of cyclic stretch resulting from blood pulsatility. Pulmonary artery endothelial cells (PAECs) produce factors that stimulate and inhib ... More
Reviewed: Reviewed
Authors: Mathivanan, Suresh | Ahmed, Mukhtar | Bj�rling, Erik | Muddiman, David C | Nali, Anuradha | Navarro, J. Daniel | Neubert, Thomas A | Ohara, Osamu | Oliva, Rafael | Omenn, Gilbert S | Oyama, Masaaki | Paik, Young-Ki | Pennington, Kyla | Blagoev, Blagoy | Pepperkok, Rainer | Periaswamy, Balamurugan | Petricoin, Emanuel F | Poirier, Guy G | Prasad, T. S. Keshava | Purvine, Samuel O | Rahiman, Abdul | Ramachandran, Prasanna | Ramachandra, Y. L | Rice, Robert H | Bose, Ron | Rick, Jens | Ronnholm, Ragna H | Salonen, Johanna | Sanchez, Jean-Charles | Sayd, Thierry | Seshi, Beerelli | Shankari, Kripa | Sheng, Shi Jun | Shetty, Vivekananda | Shivakumar, K | Brahmachari, Samir K | Simpson, Richard J | Sirdeshmukh, Ravi | Siu, K. W. Michael | Smith, Jeffrey C | Smith, Richard D | States, David J | Sugano, Sumio | Sullivan, Matthew | Superti-Furga, Giulio | Takatalo, Maarit | Burlingame, Alma S | Thongboonkerd, Visith | Trinidad, Jonathan C | Uhlen, Mathias | Vandekerckhove, Jo�l | Vasilescu, Julian | Veenstra, Timothy D | Vidal-Taboada, Jos�-Manuel | Vihinen, Mauno | Wait, Robin | Wang, Xiaoyue | Bustelo, Xos� R | Wiemann, Stefan | Wu, Billy | Xu, Tao | Yates, John R | Zhong, Jun | Zhou, Ming | Zhu, Yunping | Zurbig, Petra | Pandey, Akhilesh Pandey | Cagney, Gerard | Cantin, Greg T | Cardasis, Helene L | Celis, Julio E | Ahn, Natalie G | Chaerkady, Raghothama | Chu, Feixia | Cole, Philip A | Costello, Catherine E | Cotter, Robert J | Crockett, David | DeLany, James P | DeSouza, Leroi V | Deutsch, Eric W | Dransfield, Eric | Alexandre, Hainard | Drewes, Gerard | Droit, Arnaud | Dunn, Michael J | Elenitoba-Johnson, Kojo | Ewing, Rob M | Van Eyk, Jennifer | Faca, Vitor | Falkner, Jayson A | Fang, Xiangming | Fenselau, Catherine | Amanchy, Ramars | Figeys, Daniel | Gagn�, Pierre | Gelfi, Cecilia | Gevaert, Kris | Gimble, Jeffrey M | Gnad, Florian | Goel, Renu | Gromov, Pavel | Hanash, Samir M | Hancock, William Stephen | Andrews, Philip C | Harsha, H. C | Hart, Gerald | Hays, Faith | He, Fuchu | Hebbar, Prashantha | Helsens, Kenny | Hermeking, Heiko | Hide, Winston | Hjern�, Karin | Hochstrasser, Denis | Bader, Joel S | Hofmann, Oliver | Horn, David M | Hruban, Ralph H | Ibarrola, Nieves | James, Peter | Jensen, Ole N | Jensen, Pia Honnerup | Jung, Peter | Kandasamy, Kumaran | Kheterpal, Indu | Balgley, Brian M | Kikuno, Reiko F | Korf, Ulrike | K�rner, Roman | Kuster, Bernhard | Kwon, Min-Seok | Lee, Hyoung-Joo | Lee, Young-Jin | Lefevre, Michael | Lehvaslaiho, Minna | Lescuyer, Pierre | Bantscheff, Marcus | Levander, Fredrik | Lim, Megan S | L�bke, Christian | Loo, Joseph A | Mann, Matthias | Martens, Lennart | Martinez-Heredia, Juan | McComb, Mark | McRedmond, James | Mehrle, Alexander | Bennett, Keiryn L | Menon, Rajasree | Miller, Christine A | Mischak, Harald | Mohan, S. Sujatha | Mohmood, Riaz | Molina, Henrik | Moran, Michael F | Morgan, James D | Moritz, Robert L | Morzel, Martine
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1186530
Description: 4 page(s)
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1132528
Description: 10 page(s)
Reviewed: Reviewed
Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117607
Description: We report on the preparation of an improved multi-lectin affinity support for HPLC separations. We combined the selectivity of three different lectins: concanavalin A (ConA), wheat germ agglutinin (WG ... More
Reviewed: Reviewed
Date: 2007
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1117620
Description: We report on the development of a robust and relatively high-throughput method for in-depth proteomic analysis of human plasma suitable for biomarker discovery. The method consists of depletion of alb ... More
Reviewed: Reviewed