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Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/144465
Description: As part of a program aimed at introducing functionality onto the Tröger's base framework post-synthesis, we investigated the formylation reaction of Tröger's base analogues with Vilsmeier reagents. We ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/144455
Description: Tröger's base analogues were prepared bearing methoxy groups in the 1,7-, 2,8-, 3,9- or 4,10-positions. These compounds were converted to their dihydroxy analogues in excellent yields upon treatment w ... More
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/126175
Description: The yields of ester-functionalised Tröger's base analogues are dramatically improved by incorporating an electron-donating group on the aromatic ring and/or enhancing solubility of the aniline unit. I ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1167312
Description: A protocol for the introduction of spiro[4.5] lactone straps onto the Tröger's base scaffold has been developed. The conversion was found to be most efficient when an appropriate carboxylic acid deriv ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1167121
Description: The one-step synthesis of a series of hybrid dibenzo Tröger's base analogues bearing at least one halogen atom is described. The strategy involves a reaction between two different anilines and affords ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1167145
Description: The synthesis of six new examples of 2,8-dinitro-substituted Tröger's base analogues are reported, together with the first examples of 1,7-, 3,9- and 4,10-dinitro Tröger's base analogues and the first ... More
Reviewed: Reviewed
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