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Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1116428
Description: Purpose: Tumor-derived circulating cell–free DNA (cfDNA) is a potential alternative source from which to derive tumor mutation status. cfDNA data from four clinical studies of the BRAF inhibitor (BRAF ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.14/1108520
Description: Background: Acquired resistance (AR) to BRAF inhibitors (BRAFi) in melanoma is a near-universal phenomenon driven by numerous genetic and non-genetic alterations. Clinical implications of these AR mec ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1058198
Description: Background: Acquired resistance to BRAF inhibitors (BRAFi) is a near-universal phenomenon caused by numerous genetic and non-genetic alterations. In this study, we evaluated the spectrum, onset, patte ... More
Reviewed: Reviewed
Authors: Law, Matthew H | Bishop, D. Timothy | Pharoah, Paul D. P | Vilalta, Antonio | Calista, Donato | Landi, Giorgio | Minghetti, Paola | Arcangeli, Fabio | Bertazzi, Pier Alberto | Pastorino, Lorenza | Bruno, William | Andreotti, Virginia | Martinuzzi, Claudia | Swerdlow, Anthony J | Battistuzzi, Linda | Origone, Paola | Queirolo, Paola | Affleck, Paul | Harrison, Jane | Whittaker, Linda | Kukalizch, Kairen | Leake, Susan | Karpavicius, Birute | Haynes, Sue | Kypreou, Katerina P | Mack, Tricia | Chan, May | Taylor, Yvonne | Davies, John | King, Paul | van Nieuwpoort, Frans A | Out, Coby | van der Drift, Clasine | Bergman, Wilma | Kukutsch, Nicole | Taylor, John C | Bouwes Bavinck, Jan Nico | Bakker, Bert | ter Huurne, Jeanet | van der Rhee, Han | Bekkenk, Marcel | Snels, Dyon | van Praag, Marinus | Brochez, Lieve | Gerritsen, Rianne | Crijns, Marianne | Harland, Mark | Vasen, Hans | van Workum, Wilbert | Janssen, Bart | Janssen, Marjolein | Mulder, Suzanne | Jönsson, Göran | Borg, Åke | Måsbäck, Anna | Lundgren, Lotta | Baeckenhorn, Katja | Randerson-Moor, Juliette | Nielsen, Kari | Schmidt Casslén, Anita | Rootwelt, Helge | Bressac-de Paillerets, Brigitte | Maubec, Eve | Brossard, Myriam | Vaysse, Amaury | Mohamdi, Hamida | Jeannin, Patricia | Chaudru, Valérie | Akslen, Lars A | Chateigner, Nicolas | Corda, Eve | Lesueur, Fabienne | de Lichy, Mahaut | Andry-Benzaquen, Pascale | Bachollet, Bertrand | Bérard, Frédéric | Berthet, Pascaline | Boitier, Françoise | Bonadona, Valérie | Andresen, Per A | Bonafé, Jean-Louis | Bonnetblanc, Jean-Marie | Cambazard, Frédéric | Caron, Olivier | Caux, Frédéric | Chevrant-Breton, Jacqueline | Chompret, Agnès | Dalle, Stéphane | Demange, Liliane | Dereure, Olivier | Avril, Marie-Françoise | Doré, Martin-Xavier | Doutre, Marie-Sylvie | Dugast, Catherine | Faivre, Laurence | Grange, Florent | Humbert, Philippe | Joly, Pascal | Kerob, Delphine | Lasset, Christine | Leccia, Marie Thérèse | Azizi, Esther | Lenoir, Gilbert | Leroux, Dominique | Levang, Julien | Lipsker, Dan | Mansard, Sandrine | Martin, Ludovic | Martin-Denavit, Tanguy | Mateus, Christine | Michel, Jean-Loïc | Morel, Patrice | Lee, Jeffrey E | Bianchi Scarrà, Giovanna | Olivier-Faivre, Laurence | Perrot, Jean-Luc | Robert, Caroline | Ronger-Savle, Sandra | Sassolas, Bruno | Souteyrand, Pierre | Stoppa-Lyonnet, Dominique | Thomas, Luc | Vabres, Pierre | Wierzbicka, Eva | Brown, Kevin M | Knorr, Jilian | Ming, Michael | Mitra, Nandita | Ruffin, Althea | Van Belle, Patricia | Lubiński, Jan | Mirecka, Aneta | Ertmański, Sławomir | Hocevar, Marko | Peric, Barbara | Dȩbniak, Tadeusz | Cerkovnik, Petra | Kefford, Richard F | Schmid, Helen | Holland, Elizabeth A | Galore-Haskel, Gilli | Baron-Epel, Orna | Scope, Alon | Pavlotsky, Felix | Yakobson, Emanuel | Cohen-Manheim, Irit | Duffy, David L | Laitman, Yael | Milgrom, Roni | Shimoni, Iris | Kozlovaa, Evgeniya | Aitken, Joanne F | Armstrong, Bruce K | Giles, Graham G | Hopper, John L | Jenkins, Mark A | Visscher, Peter | Elder, David E | Webb, Penny | Green, Adele | Parsons, Peter | Purdie, David | Zhao, Zhen Zhen | Henders, Anjali K | Stark, Mitchell | Painter, Jodie N | Pavey, Sandra | Gotley, David | Fang, Shenying | Smithers, Mark | Drew, Paul | Jamieson, Glyn | Watson, David | Clouston, Andrew | Nancarrow, D | Hussey, D | Smith, E | Mayne, G | O'Brien, S | Friedman, Eitan | Sadkowsky, T | McMurtrie, A | Terry, L | Connard, M | Jackman, L | Perry, S | Davis, M | Roffe, D | Martin, M | Smith, L | Galan, Pilar | Brown, I | Walker, N | Bessell, Justin | Tam, William | Ruskowicz, Andrew | Hemminki, Kari | Sucker, Antje | Vogt, Thomas | Gutzmer, Ralf | Gogas, Helen | Ghiorzo, Paola | Hoon, David | Nagore, Eduardo | Kirkwood, John | Weide, Benjamin | Rutkowski, Piotr | Ugurel, Selma | Karagianni, Fani | Antonopoulou, Kyriaki | Polydorou, Dorothea | Hasapi, Vasiliki | Gillanders, Elizabeth M | Plaka, Michaela | Gousetti, Nelli | Papadopoulos, Othon | Antoniou, Christina | Evangelou, Vangelis | Goldstein, Alisa M | Gruis, Nelleke A | Hansson, Johan | Helsing, Per | Hočevar, Marko | Höiom, Veronica | Ingvar, Christian | Kanetsky, Peter A | Chen, Wei V | Landi, Maria Teresa | Martin, Nicholas G | Lang, Julie | Lathrop, G. Mark | Mackie, Rona M | Mann, Graham J | Molven, Anders | Montgomery, Grant W | Novaković, Srdjan | Olsson, Håkan | Puig, Susana | Moses, Eric K | Puig-Butille, Joan Anton | Qureshi, Abrar A | Radford-Smith, Graham L | van der Stoep, Nienke | van Doorn, Remco | Whiteman, David C | Craig, Jamie E | Schadendorf, Dirk | Simms, Lisa A | Burdon, Kathryn P | Song, Fengju | Nyholt, Dale R | Pooley, Karen A | Orr, Nick | Stratigos, Alexander J | Cust, Anne E | Ward, Sarah V | Hayward, Nicholas K | Han, Jiali | Schulze, Hans-Joachim | Dunning, Alison M | Barrett, Jennifer H | Newton Bishop, Julia A | Demenais, Florence | Amos, Christopher I | MacGregor, Stuart | Iles, Mark M | Aguilera, Paula | Alejo, Beatriz | Badenas, Celia | Caño, Abel | Carrera, Cristina | Kumar, Rajiv | Cuellar, Francisco | Dominguez, Mireia | Gabriel, Daniel | Gimenez-Xavier, Pol | Iglesias, Pablo | Malvehy, Josep | Marti-Laborda, Rosa | Mila, Montse | Ogbah, Zighe | Potrony, Miriam | Easton, Douglas F | Tell, Gemma | Alós, Llúcia | Arance, Ana | Arguís, Pedro | Bennassar, Antonio | Chirife, Oscar | Conill, Carlos | Rull, Ramon | Sánchez, Marcelo | Vidal-Sicart, Sergi
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1070416
Description: Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide associ ... More
Reviewed: Reviewed
Authors: Akbani, Rehan | Akdemir, Kadir C | Baboud, Julien | Gomez-Fernandez, Carmen | Gribbin, Thomas | Grimsby, Jonna | Gross, Benjamin | Guin, Ranabir | Gutschner, Tony | Hadjipanayis, Angela | Halaban, Ruth | Hanf, Benjamin | Haussler, David | Balasundaram, Miruna | Haydu, Lauren E | Hayes, D. Neil | Hayward, Nicholas K | Heiman, David I | Herbert, Lynn | Herman, James G | Hersey, Peter | Hoadley, Katherine A | Hodis, Eran | Holt, Robert A | Balu, Saianand | Hoon, Dave S. B | Hoppough, Susan | Hoyle, Alan P | Huang, Franklin W | Huang, Mei | Huang, Sharon | Hutter, Carolyn M | Ibbs, Matthew | Iype, Lisa | Jacobsen, Anders | Barnabas, Nandita | Jakrot, Valerie | Janning, Alyssa | Jeck, William R | Jefferys, Stuart R | Jensen, Mark A | Jones, Corbin D | Jones, Steven J. M | Ju, Zhenlin | Kakavand, Hojabr | Kang, Hyojin | Bartlett, John | Kefford, Richard F | Khuri, Fadio R | Kim, Jaegil | Kirkwood, John M | Klode, Joachim | Korkut, Anil | Korski, Konstanty | Krauthammer, Michael | Kucherlapati, Raju | Kwong, Lawrence N | Bartlett, Pam | Kycler, Witold | Ladanyi, Marc | Lai, Phillip H | Laird, Peter W | Lander, Eric | Lawrence, Michael S | Lazar, Alexander J | Łaźniak, Radoslaw | Lee, Darlene | Lee, Jeffrey E | Bastian, Boris C | Lee, Junehawk | Lee, Kenneth | Lee, Semin | Lee, William | Leporowska, Ewa | Leraas, Kristen M | Li, Haiyan I | Lichtenberg, Tara M | Lichtenstein, Lee | Lin, Pei | Baylin, Stephen B | Ling, Shiyun | Liu, Jia | Liu, Ouida | Liu, Wenbin | Long, Georgina V | Lu, Yiling | Ma, Singer | Ma, Yussanne | Mackiewicz, Andrzej | Mahadeshwar, Harshad S | Behera, Madhusmita | Malke, Jared | Mallery, David | Manikhas, Georgy M | Mann, Graham J | Marra, Marco A | Matejka, Brenna | Mayo, Michael | Mehrabi, Sousan | Meng, Shaowu | Meyerson, Matthew | Belyaev, Dmitry | Mieczkowski, Piotr A | Miller, John P | Miller, Martin L | Mills, Gordon B | Moiseenko, Fedor | Moore, Richard A | Morris, Scott | Morrison, Carl | Morton, Donald L | Moschos, Stergios | Aksoy, B. Arman | Benz, Christopher | Mose, Lisle E | Muller, Florian L | Mungall, Andrew J | Murawa, Dawid | Murawa, Pawel | Murray, Bradley A | Nezi, Luigi | Ng, Sam | Nicholson, Dana | Noble, Michael S | Bernard, Brady | Osunkoya, Adeboye | Owonikoko, Taofeek K | Ozenberger, Bradley A | Pagani, Elena | Paklina, Oxana V | Pantazi, Angeliki | Parfenov, Michael | Parfitt, Jeremy | Park, Peter J | Park, Woong-Yang | Beroukhim, Rameen | Parker, Joel S | Passarelli, Francesca | Penny, Robert | Perou, Charles M | Pihl, Todd D | Potapova, Olga | Prieto, Victor G | Protopopov, Alexei | Quinn, Michael J | Radenbaugh, Amie | Bir, Natalie | Rai, Kunal | Ramalingam, Suresh S | Raman, Ayush T | Ramirez, Nilsa C | Ramirez, Ricardo | Rao, Uma | Rathmell, W. Kimryn | Ren, Xiaojia | Reynolds, Sheila M | Roach, Jeffrey | Black, Aaron D | Robertson, A. Gordon | Ross, Merrick I | Roszik, Jason | Russo, Giandomenico | Saksena, Gordon | Saller, Charles | Samuels, Yardena | Sander, Chris | Sander, Cindy | Sandusky, George | Bodenheimer, Tom | Santoso, Netty | Saul, Melissa | Saw, Robyn P. M | Schadendorf, Dirk | Schein, Jacqueline E | Schultz, Nikolaus | Schumacher, Steven E | Schwallier, Charles | Scolyer, Richard A | Seidman, Jonathan | Boice, Lori | Sekhar, Pedamallu Chandra | Sekhon, Harmanjatinder S | Senbabaoglu, Yasin | Seth, Sahil | Shannon, Kerwin F | Sharpe, Samantha | Sharpless, Norman E | Shaw, Kenna R. Mills | Shelton, Candace | Shelton, Troy | Boland, Genevieve M | Shen, Ronglai | Sheth, Margi | Shi, Yan | Shiau, Carolyn J | Shmulevich, Ilya | Sica, Gabriel L | Simons, Janae V | Sinha, Rileen | Sipahimalani, Payal | Sofia, Heidi J | Bono, Riccardo | Soloway, Matthew G | Song, Xingzhi | Sougnez, Carrie | Spillane, Andrew J | Spychala, Arkadiusz | Stretch, Jonathan R | Stuart, Joshua | Suchorska, Wiktoria M | Sucker, Antje | Sumer, S. Onur | Bootwalla, Moiz S | Sun, Yichao | Synott, Maria | Tabak, Barbara | Tabler, Teresa R | Tam, Angela | Tan, Donghui | Tang, Jiabin | Tarnuzzer, Roy | Tarvin, Katherine | Tatka, Honorata | Albert, Monique | Bosenberg, Marcus | Taylor, Barry S | Teresiak, Marek | Thiessen, Nina | Thompson, John F | Thorne, Leigh | Thorsson, Vesteinn | Trent, Jeffrey M | Triche Jr., Timothy J | Tsai, Kenneth Y | Tsou, Peiling | Bowen, Jay | Van Den Berg, David J | Van Allen, Eliezer M | Veluvolu, Umadevi | Verhaak, Roeland G | Voet, Douglas | Voronina, Olga | Walter, Vonn | Walton, Jessica S | Wan, Yunhu | Wang, Yuling | Bowlby, Reanne | Wang, Zhining | Waring, Scot | Watson, Ian R | Weinhold, Nils | Weinstein, John N | Weisenberger, Daniel J | White, Peter | Wilkerson, Matthew D | Wilmott, James S | Wise, Lisa | Bristow, Christopher A | Wiznerowicz, Maciej | Woodman, Scott E | Wu, Chang-Jiun | Wu, Chia-Chin | Wu, Junyuan | Wu, Ye | Xi, Ruibin | Xu, Andrew Wei | Yang, Da | Yang, Liming | Brockway-Lunardi, Laura | Yang, Lixing | Zack, Travis I | Zenklusen, Jean C | Zhang, Hailei | Zhang, Jianhua | Zhang, Wei | Zhao, Xiaobei | Zhu, Jingchun | Zhu, Kelsey | Zimmer, Lisa | Brooks, Denise | Zmuda, Erik | Zou, Lihua | Brzezinski, Jakub | Bshara, Wiam | Buda, Elizabeth | Burns, William R | Ally, Adrian | Butterfield, Yaron S. N | Button, Michael | Calderone, Tiffany | Cappellini, Giancarlo Antonini | Carter, Candace | Carter, Scott L | Cherney, Lynn | Cherniack, Andrew D | Chevalier, Aaron | Chin, Lynda | Amin, Samirkumar B | Cho, Juok | Cho, Raymond J | Choi, Yoon-La | Chu, Andy | Chudamani, Sudha | Cibulskis, Kristian | Ciriello, Giovanni | Clarke, Amanda | Coons, Stephen | Cope, Leslie | Arachchi, Harindra | Crain, Daniel | Curley, Erin | Danilova, Ludmila | D'Atri, Stefania | Davidsen, Tanja | Davies, Michael A | Delman, Keith A | Demchok, John A | Deng, Qixia A | Deribe, Yonathan Lissanu | Arora, Arshi | Dhalla, Noreen | Dhir, Rajiv | DiCara, Daniel | Dinikin, Michael | Dubina, Michael | Ebrom, J. Stephen | Egea, Sophie | Eley, Greg | Engel, Jay | Eschbacher, Jennifer M | Auman, J. Todd | Fedosenko, Konstantin V | Felau, Ina | Fennell, Timothy | Ferguson, Martin L | Fisher, Sheila | Flaherty, Keith T | Frazer, Scott | Frick, Jessica | Fulidou, Victoria | Gabriel, Stacey B | Ayala, Brenda | Gao, Jianjiong | Gardner, Johanna | Garraway, Levi A | Gastier-Foster, Julie M | Gaudioso, Carmelo | Gehlenborg, Nils | Genovese, Gianicola | Gerken, Mark | Gershenwald, Jeffrey E | Getz, Gad
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1062489
Description: We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients. We establish a framew ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1059706
Description: The molecular classification of melanoma and the advent of new drugs are changing the paradigm of therapy for advanced melanoma. A review of the recent key studies was performed, followed by a discuss ... More
Reviewed: Reviewed
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/340789
Description: Purpose: New primary melanomas (NPMs) have developed in some patients with metastatic melanoma treated with BRAF inhibitors. We sought to determine the background incidence of spontaneous NPMs after a ... More
Reviewed: Reviewed
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1110617
Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/340689
Description: Background: Recent phase 3 trials have shown an overall survival benefit in metastatic melanoma. We aimed to assess whether progression-free survival (PFS) could be regarded as a reliable surrogate fo ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/293533
Description: Dabrafenib (GSK2118436) is a potent inhibitor of mutated BRAF kinase. Our multicenter, single-arm, phase II study assessed the safety and clinical activity of dabrafenib in BRAF(V600E/K) mutation-posi ... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294579
Description: Background: Brain metastases are common in patients with metastatic melanoma and median overall survival from their diagnosis is typically 17-22 weeks. We assessed dabrafenib in patients with Val600Gl ... More
Reviewed: Reviewed
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