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Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1115129
Description: Targeted therapy directed at driver oncogenic mutations offers an effective treatment option for select patients with metastatic melanoma. The aim of this study was to assess the prevalence of clinica ... More
Reviewed: Reviewed
Authors: Akbani, Rehan | Akdemir, Kadir C | Baboud, Julien | Gomez-Fernandez, Carmen | Gribbin, Thomas | Grimsby, Jonna | Gross, Benjamin | Guin, Ranabir | Gutschner, Tony | Hadjipanayis, Angela | Halaban, Ruth | Hanf, Benjamin | Haussler, David | Balasundaram, Miruna | Haydu, Lauren E | Hayes, D. Neil | Hayward, Nicholas K | Heiman, David I | Herbert, Lynn | Herman, James G | Hersey, Peter | Hoadley, Katherine A | Hodis, Eran | Holt, Robert A | Balu, Saianand | Hoon, Dave S. B | Hoppough, Susan | Hoyle, Alan P | Huang, Franklin W | Huang, Mei | Huang, Sharon | Hutter, Carolyn M | Ibbs, Matthew | Iype, Lisa | Jacobsen, Anders | Barnabas, Nandita | Jakrot, Valerie | Janning, Alyssa | Jeck, William R | Jefferys, Stuart R | Jensen, Mark A | Jones, Corbin D | Jones, Steven J. M | Ju, Zhenlin | Kakavand, Hojabr | Kang, Hyojin | Bartlett, John | Kefford, Richard F | Khuri, Fadio R | Kim, Jaegil | Kirkwood, John M | Klode, Joachim | Korkut, Anil | Korski, Konstanty | Krauthammer, Michael | Kucherlapati, Raju | Kwong, Lawrence N | Bartlett, Pam | Kycler, Witold | Ladanyi, Marc | Lai, Phillip H | Laird, Peter W | Lander, Eric | Lawrence, Michael S | Lazar, Alexander J | Łaźniak, Radoslaw | Lee, Darlene | Lee, Jeffrey E | Bastian, Boris C | Lee, Junehawk | Lee, Kenneth | Lee, Semin | Lee, William | Leporowska, Ewa | Leraas, Kristen M | Li, Haiyan I | Lichtenberg, Tara M | Lichtenstein, Lee | Lin, Pei | Baylin, Stephen B | Ling, Shiyun | Liu, Jia | Liu, Ouida | Liu, Wenbin | Long, Georgina V | Lu, Yiling | Ma, Singer | Ma, Yussanne | Mackiewicz, Andrzej | Mahadeshwar, Harshad S | Behera, Madhusmita | Malke, Jared | Mallery, David | Manikhas, Georgy M | Mann, Graham J | Marra, Marco A | Matejka, Brenna | Mayo, Michael | Mehrabi, Sousan | Meng, Shaowu | Meyerson, Matthew | Belyaev, Dmitry | Mieczkowski, Piotr A | Miller, John P | Miller, Martin L | Mills, Gordon B | Moiseenko, Fedor | Moore, Richard A | Morris, Scott | Morrison, Carl | Morton, Donald L | Moschos, Stergios | Aksoy, B. Arman | Benz, Christopher | Mose, Lisle E | Muller, Florian L | Mungall, Andrew J | Murawa, Dawid | Murawa, Pawel | Murray, Bradley A | Nezi, Luigi | Ng, Sam | Nicholson, Dana | Noble, Michael S | Bernard, Brady | Osunkoya, Adeboye | Owonikoko, Taofeek K | Ozenberger, Bradley A | Pagani, Elena | Paklina, Oxana V | Pantazi, Angeliki | Parfenov, Michael | Parfitt, Jeremy | Park, Peter J | Park, Woong-Yang | Beroukhim, Rameen | Parker, Joel S | Passarelli, Francesca | Penny, Robert | Perou, Charles M | Pihl, Todd D | Potapova, Olga | Prieto, Victor G | Protopopov, Alexei | Quinn, Michael J | Radenbaugh, Amie | Bir, Natalie | Rai, Kunal | Ramalingam, Suresh S | Raman, Ayush T | Ramirez, Nilsa C | Ramirez, Ricardo | Rao, Uma | Rathmell, W. Kimryn | Ren, Xiaojia | Reynolds, Sheila M | Roach, Jeffrey | Black, Aaron D | Robertson, A. Gordon | Ross, Merrick I | Roszik, Jason | Russo, Giandomenico | Saksena, Gordon | Saller, Charles | Samuels, Yardena | Sander, Chris | Sander, Cindy | Sandusky, George | Bodenheimer, Tom | Santoso, Netty | Saul, Melissa | Saw, Robyn P. M | Schadendorf, Dirk | Schein, Jacqueline E | Schultz, Nikolaus | Schumacher, Steven E | Schwallier, Charles | Scolyer, Richard A | Seidman, Jonathan | Boice, Lori | Sekhar, Pedamallu Chandra | Sekhon, Harmanjatinder S | Senbabaoglu, Yasin | Seth, Sahil | Shannon, Kerwin F | Sharpe, Samantha | Sharpless, Norman E | Shaw, Kenna R. Mills | Shelton, Candace | Shelton, Troy | Boland, Genevieve M | Shen, Ronglai | Sheth, Margi | Shi, Yan | Shiau, Carolyn J | Shmulevich, Ilya | Sica, Gabriel L | Simons, Janae V | Sinha, Rileen | Sipahimalani, Payal | Sofia, Heidi J | Bono, Riccardo | Soloway, Matthew G | Song, Xingzhi | Sougnez, Carrie | Spillane, Andrew J | Spychala, Arkadiusz | Stretch, Jonathan R | Stuart, Joshua | Suchorska, Wiktoria M | Sucker, Antje | Sumer, S. Onur | Bootwalla, Moiz S | Sun, Yichao | Synott, Maria | Tabak, Barbara | Tabler, Teresa R | Tam, Angela | Tan, Donghui | Tang, Jiabin | Tarnuzzer, Roy | Tarvin, Katherine | Tatka, Honorata | Albert, Monique | Bosenberg, Marcus | Taylor, Barry S | Teresiak, Marek | Thiessen, Nina | Thompson, John F | Thorne, Leigh | Thorsson, Vesteinn | Trent, Jeffrey M | Triche Jr., Timothy J | Tsai, Kenneth Y | Tsou, Peiling | Bowen, Jay | Van Den Berg, David J | Van Allen, Eliezer M | Veluvolu, Umadevi | Verhaak, Roeland G | Voet, Douglas | Voronina, Olga | Walter, Vonn | Walton, Jessica S | Wan, Yunhu | Wang, Yuling | Bowlby, Reanne | Wang, Zhining | Waring, Scot | Watson, Ian R | Weinhold, Nils | Weinstein, John N | Weisenberger, Daniel J | White, Peter | Wilkerson, Matthew D | Wilmott, James S | Wise, Lisa | Bristow, Christopher A | Wiznerowicz, Maciej | Woodman, Scott E | Wu, Chang-Jiun | Wu, Chia-Chin | Wu, Junyuan | Wu, Ye | Xi, Ruibin | Xu, Andrew Wei | Yang, Da | Yang, Liming | Brockway-Lunardi, Laura | Yang, Lixing | Zack, Travis I | Zenklusen, Jean C | Zhang, Hailei | Zhang, Jianhua | Zhang, Wei | Zhao, Xiaobei | Zhu, Jingchun | Zhu, Kelsey | Zimmer, Lisa | Brooks, Denise | Zmuda, Erik | Zou, Lihua | Brzezinski, Jakub | Bshara, Wiam | Buda, Elizabeth | Burns, William R | Ally, Adrian | Butterfield, Yaron S. N | Button, Michael | Calderone, Tiffany | Cappellini, Giancarlo Antonini | Carter, Candace | Carter, Scott L | Cherney, Lynn | Cherniack, Andrew D | Chevalier, Aaron | Chin, Lynda | Amin, Samirkumar B | Cho, Juok | Cho, Raymond J | Choi, Yoon-La | Chu, Andy | Chudamani, Sudha | Cibulskis, Kristian | Ciriello, Giovanni | Clarke, Amanda | Coons, Stephen | Cope, Leslie | Arachchi, Harindra | Crain, Daniel | Curley, Erin | Danilova, Ludmila | D'Atri, Stefania | Davidsen, Tanja | Davies, Michael A | Delman, Keith A | Demchok, John A | Deng, Qixia A | Deribe, Yonathan Lissanu | Arora, Arshi | Dhalla, Noreen | Dhir, Rajiv | DiCara, Daniel | Dinikin, Michael | Dubina, Michael | Ebrom, J. Stephen | Egea, Sophie | Eley, Greg | Engel, Jay | Eschbacher, Jennifer M | Auman, J. Todd | Fedosenko, Konstantin V | Felau, Ina | Fennell, Timothy | Ferguson, Martin L | Fisher, Sheila | Flaherty, Keith T | Frazer, Scott | Frick, Jessica | Fulidou, Victoria | Gabriel, Stacey B | Ayala, Brenda | Gao, Jianjiong | Gardner, Johanna | Garraway, Levi A | Gastier-Foster, Julie M | Gaudioso, Carmelo | Gehlenborg, Nils | Genovese, Gianicola | Gerken, Mark | Gershenwald, Jeffrey E | Getz, Gad
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1062489
Description: We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients. We establish a framew ... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294242
Description: Prediction of outcome for melanoma patients with surgically resected macroscopic nodal metastases is very imprecise. We performed a comprehensive clinico-pathologic assessment of fresh-frozen macrosco ... More
Reviewed: Reviewed
Date: 2013
Subject Keyword: 110300 Clinical Sciences
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/293557
Description: Approximately 50% of melanomas require oncogenic B-RAF V600E signaling for proliferation, survival, and metastasis, and the use of highly selective B-RAF inhibitors has yielded remarkable, although sh ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294838
Description: Purpose: To assess the frequency and type of oncogenic BRAF mutations in metastatic melanoma and correlate BRAF status with clinicopathologic features and outcome. Patients and Methods: Consecutive BR ... More
Reviewed: Reviewed
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/294845
Description: 4 page(s)
Reviewed: Reviewed
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/295056
Description: Induction of senescence permanently restricts cellular proliferation after oncogenic stimulation thereby acting as a potent barrier to tumor development. The relevant effector proteins may therefore b ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/295085
Description: Background: CDKN2A/p16INK4a is frequently altered in human cancers and it is the most important melanoma susceptibility gene identified to date. p16INK4a inhibits pRb phosphorylation and induces cell ... More
Reviewed: Reviewed
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