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Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1111836
Description: We report the occurrence of autoimmune hemolytic anemia in a patient receiving the anti-PD-1 monoclonal antibody, nivolumab, for metastatic melanoma in the presence of known red cell alloantibodies, d ... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1200751
Description: Background: It is unknown whether melanoma patients achieving complete response (CR) with targeted therapy can safely discontinue treatment. Methods: All patients treated with BRAF/MEK inhibitors achi ... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1196756
Description: Importance: Identifying individuals at high risk of melanoma can optimize primary and secondary prevention strategies. Objective: To develop and externally validate a risk prediction model for inciden ... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1114220
Description: Purpose To report the overall survival (OS) and clinical characteristics of BRAF inhibitor–naive long-term responders and survivors treated with dabrafenib plus trametinib in a phase I and II study of ... More
Reviewed: Reviewed
Date: 2016
Subject Keyword: FDG-PET | anti-PD-1 | melanoma | nivolumab | pembrolizumab
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1183968
Description: 18-Fluorodeoxyglucose positron emission tomography (FDG-PET) scans were performed on 27 patients with unresectable stage IIIC or IV melanoma after prolonged treatment with anti-PD-1 antibodies to exam ... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1115129
Description: Targeted therapy directed at driver oncogenic mutations offers an effective treatment option for select patients with metastatic melanoma. The aim of this study was to assess the prevalence of clinica ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1058198
Description: Background: Acquired resistance to BRAF inhibitors (BRAFi) is a near-universal phenomenon caused by numerous genetic and non-genetic alterations. In this study, we evaluated the spectrum, onset, patte ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1060133
Description: We report the acute onset of polyarticular inflammatory arthritis in 2 patients receiving the immune check-point inhibitor, pembrolizumab (MK-3475), anti-PD1 drug for metastatic melanoma after 14 and ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1048538
Description: Background: The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic fact ... More
Reviewed: Reviewed
Authors: Law, Matthew H | Bishop, D. Timothy | Pharoah, Paul D. P | Vilalta, Antonio | Calista, Donato | Landi, Giorgio | Minghetti, Paola | Arcangeli, Fabio | Bertazzi, Pier Alberto | Pastorino, Lorenza | Bruno, William | Andreotti, Virginia | Martinuzzi, Claudia | Swerdlow, Anthony J | Battistuzzi, Linda | Origone, Paola | Queirolo, Paola | Affleck, Paul | Harrison, Jane | Whittaker, Linda | Kukalizch, Kairen | Leake, Susan | Karpavicius, Birute | Haynes, Sue | Kypreou, Katerina P | Mack, Tricia | Chan, May | Taylor, Yvonne | Davies, John | King, Paul | van Nieuwpoort, Frans A | Out, Coby | van der Drift, Clasine | Bergman, Wilma | Kukutsch, Nicole | Taylor, John C | Bouwes Bavinck, Jan Nico | Bakker, Bert | ter Huurne, Jeanet | van der Rhee, Han | Bekkenk, Marcel | Snels, Dyon | van Praag, Marinus | Brochez, Lieve | Gerritsen, Rianne | Crijns, Marianne | Harland, Mark | Vasen, Hans | van Workum, Wilbert | Janssen, Bart | Janssen, Marjolein | Mulder, Suzanne | Jönsson, Göran | Borg, Åke | Måsbäck, Anna | Lundgren, Lotta | Baeckenhorn, Katja | Randerson-Moor, Juliette | Nielsen, Kari | Schmidt Casslén, Anita | Rootwelt, Helge | Bressac-de Paillerets, Brigitte | Maubec, Eve | Brossard, Myriam | Vaysse, Amaury | Mohamdi, Hamida | Jeannin, Patricia | Chaudru, Valérie | Akslen, Lars A | Chateigner, Nicolas | Corda, Eve | Lesueur, Fabienne | de Lichy, Mahaut | Andry-Benzaquen, Pascale | Bachollet, Bertrand | Bérard, Frédéric | Berthet, Pascaline | Boitier, Françoise | Bonadona, Valérie | Andresen, Per A | Bonafé, Jean-Louis | Bonnetblanc, Jean-Marie | Cambazard, Frédéric | Caron, Olivier | Caux, Frédéric | Chevrant-Breton, Jacqueline | Chompret, Agnès | Dalle, Stéphane | Demange, Liliane | Dereure, Olivier | Avril, Marie-Françoise | Doré, Martin-Xavier | Doutre, Marie-Sylvie | Dugast, Catherine | Faivre, Laurence | Grange, Florent | Humbert, Philippe | Joly, Pascal | Kerob, Delphine | Lasset, Christine | Leccia, Marie Thérèse | Azizi, Esther | Lenoir, Gilbert | Leroux, Dominique | Levang, Julien | Lipsker, Dan | Mansard, Sandrine | Martin, Ludovic | Martin-Denavit, Tanguy | Mateus, Christine | Michel, Jean-Loïc | Morel, Patrice | Lee, Jeffrey E | Bianchi Scarrà, Giovanna | Olivier-Faivre, Laurence | Perrot, Jean-Luc | Robert, Caroline | Ronger-Savle, Sandra | Sassolas, Bruno | Souteyrand, Pierre | Stoppa-Lyonnet, Dominique | Thomas, Luc | Vabres, Pierre | Wierzbicka, Eva | Brown, Kevin M | Knorr, Jilian | Ming, Michael | Mitra, Nandita | Ruffin, Althea | Van Belle, Patricia | Lubiński, Jan | Mirecka, Aneta | Ertmański, Sławomir | Hocevar, Marko | Peric, Barbara | Dȩbniak, Tadeusz | Cerkovnik, Petra | Kefford, Richard F | Schmid, Helen | Holland, Elizabeth A | Galore-Haskel, Gilli | Baron-Epel, Orna | Scope, Alon | Pavlotsky, Felix | Yakobson, Emanuel | Cohen-Manheim, Irit | Duffy, David L | Laitman, Yael | Milgrom, Roni | Shimoni, Iris | Kozlovaa, Evgeniya | Aitken, Joanne F | Armstrong, Bruce K | Giles, Graham G | Hopper, John L | Jenkins, Mark A | Visscher, Peter | Elder, David E | Webb, Penny | Green, Adele | Parsons, Peter | Purdie, David | Zhao, Zhen Zhen | Henders, Anjali K | Stark, Mitchell | Painter, Jodie N | Pavey, Sandra | Gotley, David | Fang, Shenying | Smithers, Mark | Drew, Paul | Jamieson, Glyn | Watson, David | Clouston, Andrew | Nancarrow, D | Hussey, D | Smith, E | Mayne, G | O'Brien, S | Friedman, Eitan | Sadkowsky, T | McMurtrie, A | Terry, L | Connard, M | Jackman, L | Perry, S | Davis, M | Roffe, D | Martin, M | Smith, L | Galan, Pilar | Brown, I | Walker, N | Bessell, Justin | Tam, William | Ruskowicz, Andrew | Hemminki, Kari | Sucker, Antje | Vogt, Thomas | Gutzmer, Ralf | Gogas, Helen | Ghiorzo, Paola | Hoon, David | Nagore, Eduardo | Kirkwood, John | Weide, Benjamin | Rutkowski, Piotr | Ugurel, Selma | Karagianni, Fani | Antonopoulou, Kyriaki | Polydorou, Dorothea | Hasapi, Vasiliki | Gillanders, Elizabeth M | Plaka, Michaela | Gousetti, Nelli | Papadopoulos, Othon | Antoniou, Christina | Evangelou, Vangelis | Goldstein, Alisa M | Gruis, Nelleke A | Hansson, Johan | Helsing, Per | Hočevar, Marko | Höiom, Veronica | Ingvar, Christian | Kanetsky, Peter A | Chen, Wei V | Landi, Maria Teresa | Martin, Nicholas G | Lang, Julie | Lathrop, G. Mark | Mackie, Rona M | Mann, Graham J | Molven, Anders | Montgomery, Grant W | Novaković, Srdjan | Olsson, Håkan | Puig, Susana | Moses, Eric K | Puig-Butille, Joan Anton | Qureshi, Abrar A | Radford-Smith, Graham L | van der Stoep, Nienke | van Doorn, Remco | Whiteman, David C | Craig, Jamie E | Schadendorf, Dirk | Simms, Lisa A | Burdon, Kathryn P | Song, Fengju | Nyholt, Dale R | Pooley, Karen A | Orr, Nick | Stratigos, Alexander J | Cust, Anne E | Ward, Sarah V | Hayward, Nicholas K | Han, Jiali | Schulze, Hans-Joachim | Dunning, Alison M | Barrett, Jennifer H | Newton Bishop, Julia A | Demenais, Florence | Amos, Christopher I | MacGregor, Stuart | Iles, Mark M | Aguilera, Paula | Alejo, Beatriz | Badenas, Celia | Caño, Abel | Carrera, Cristina | Kumar, Rajiv | Cuellar, Francisco | Dominguez, Mireia | Gabriel, Daniel | Gimenez-Xavier, Pol | Iglesias, Pablo | Malvehy, Josep | Marti-Laborda, Rosa | Mila, Montse | Ogbah, Zighe | Potrony, Miriam | Easton, Douglas F | Tell, Gemma | Alós, Llúcia | Arance, Ana | Arguís, Pedro | Bennassar, Antonio | Chirife, Oscar | Conill, Carlos | Rull, Ramon | Sánchez, Marcelo | Vidal-Sicart, Sergi
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1070416
Description: Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide associ ... More
Reviewed: Reviewed
Authors: Akbani, Rehan | Akdemir, Kadir C | Baboud, Julien | Gomez-Fernandez, Carmen | Gribbin, Thomas | Grimsby, Jonna | Gross, Benjamin | Guin, Ranabir | Gutschner, Tony | Hadjipanayis, Angela | Halaban, Ruth | Hanf, Benjamin | Haussler, David | Balasundaram, Miruna | Haydu, Lauren E | Hayes, D. Neil | Hayward, Nicholas K | Heiman, David I | Herbert, Lynn | Herman, James G | Hersey, Peter | Hoadley, Katherine A | Hodis, Eran | Holt, Robert A | Balu, Saianand | Hoon, Dave S. B | Hoppough, Susan | Hoyle, Alan P | Huang, Franklin W | Huang, Mei | Huang, Sharon | Hutter, Carolyn M | Ibbs, Matthew | Iype, Lisa | Jacobsen, Anders | Barnabas, Nandita | Jakrot, Valerie | Janning, Alyssa | Jeck, William R | Jefferys, Stuart R | Jensen, Mark A | Jones, Corbin D | Jones, Steven J. M | Ju, Zhenlin | Kakavand, Hojabr | Kang, Hyojin | Bartlett, John | Kefford, Richard F | Khuri, Fadio R | Kim, Jaegil | Kirkwood, John M | Klode, Joachim | Korkut, Anil | Korski, Konstanty | Krauthammer, Michael | Kucherlapati, Raju | Kwong, Lawrence N | Bartlett, Pam | Kycler, Witold | Ladanyi, Marc | Lai, Phillip H | Laird, Peter W | Lander, Eric | Lawrence, Michael S | Lazar, Alexander J | Łaźniak, Radoslaw | Lee, Darlene | Lee, Jeffrey E | Bastian, Boris C | Lee, Junehawk | Lee, Kenneth | Lee, Semin | Lee, William | Leporowska, Ewa | Leraas, Kristen M | Li, Haiyan I | Lichtenberg, Tara M | Lichtenstein, Lee | Lin, Pei | Baylin, Stephen B | Ling, Shiyun | Liu, Jia | Liu, Ouida | Liu, Wenbin | Long, Georgina V | Lu, Yiling | Ma, Singer | Ma, Yussanne | Mackiewicz, Andrzej | Mahadeshwar, Harshad S | Behera, Madhusmita | Malke, Jared | Mallery, David | Manikhas, Georgy M | Mann, Graham J | Marra, Marco A | Matejka, Brenna | Mayo, Michael | Mehrabi, Sousan | Meng, Shaowu | Meyerson, Matthew | Belyaev, Dmitry | Mieczkowski, Piotr A | Miller, John P | Miller, Martin L | Mills, Gordon B | Moiseenko, Fedor | Moore, Richard A | Morris, Scott | Morrison, Carl | Morton, Donald L | Moschos, Stergios | Aksoy, B. Arman | Benz, Christopher | Mose, Lisle E | Muller, Florian L | Mungall, Andrew J | Murawa, Dawid | Murawa, Pawel | Murray, Bradley A | Nezi, Luigi | Ng, Sam | Nicholson, Dana | Noble, Michael S | Bernard, Brady | Osunkoya, Adeboye | Owonikoko, Taofeek K | Ozenberger, Bradley A | Pagani, Elena | Paklina, Oxana V | Pantazi, Angeliki | Parfenov, Michael | Parfitt, Jeremy | Park, Peter J | Park, Woong-Yang | Beroukhim, Rameen | Parker, Joel S | Passarelli, Francesca | Penny, Robert | Perou, Charles M | Pihl, Todd D | Potapova, Olga | Prieto, Victor G | Protopopov, Alexei | Quinn, Michael J | Radenbaugh, Amie | Bir, Natalie | Rai, Kunal | Ramalingam, Suresh S | Raman, Ayush T | Ramirez, Nilsa C | Ramirez, Ricardo | Rao, Uma | Rathmell, W. Kimryn | Ren, Xiaojia | Reynolds, Sheila M | Roach, Jeffrey | Black, Aaron D | Robertson, A. Gordon | Ross, Merrick I | Roszik, Jason | Russo, Giandomenico | Saksena, Gordon | Saller, Charles | Samuels, Yardena | Sander, Chris | Sander, Cindy | Sandusky, George | Bodenheimer, Tom | Santoso, Netty | Saul, Melissa | Saw, Robyn P. M | Schadendorf, Dirk | Schein, Jacqueline E | Schultz, Nikolaus | Schumacher, Steven E | Schwallier, Charles | Scolyer, Richard A | Seidman, Jonathan | Boice, Lori | Sekhar, Pedamallu Chandra | Sekhon, Harmanjatinder S | Senbabaoglu, Yasin | Seth, Sahil | Shannon, Kerwin F | Sharpe, Samantha | Sharpless, Norman E | Shaw, Kenna R. Mills | Shelton, Candace | Shelton, Troy | Boland, Genevieve M | Shen, Ronglai | Sheth, Margi | Shi, Yan | Shiau, Carolyn J | Shmulevich, Ilya | Sica, Gabriel L | Simons, Janae V | Sinha, Rileen | Sipahimalani, Payal | Sofia, Heidi J | Bono, Riccardo | Soloway, Matthew G | Song, Xingzhi | Sougnez, Carrie | Spillane, Andrew J | Spychala, Arkadiusz | Stretch, Jonathan R | Stuart, Joshua | Suchorska, Wiktoria M | Sucker, Antje | Sumer, S. Onur | Bootwalla, Moiz S | Sun, Yichao | Synott, Maria | Tabak, Barbara | Tabler, Teresa R | Tam, Angela | Tan, Donghui | Tang, Jiabin | Tarnuzzer, Roy | Tarvin, Katherine | Tatka, Honorata | Albert, Monique | Bosenberg, Marcus | Taylor, Barry S | Teresiak, Marek | Thiessen, Nina | Thompson, John F | Thorne, Leigh | Thorsson, Vesteinn | Trent, Jeffrey M | Triche Jr., Timothy J | Tsai, Kenneth Y | Tsou, Peiling | Bowen, Jay | Van Den Berg, David J | Van Allen, Eliezer M | Veluvolu, Umadevi | Verhaak, Roeland G | Voet, Douglas | Voronina, Olga | Walter, Vonn | Walton, Jessica S | Wan, Yunhu | Wang, Yuling | Bowlby, Reanne | Wang, Zhining | Waring, Scot | Watson, Ian R | Weinhold, Nils | Weinstein, John N | Weisenberger, Daniel J | White, Peter | Wilkerson, Matthew D | Wilmott, James S | Wise, Lisa | Bristow, Christopher A | Wiznerowicz, Maciej | Woodman, Scott E | Wu, Chang-Jiun | Wu, Chia-Chin | Wu, Junyuan | Wu, Ye | Xi, Ruibin | Xu, Andrew Wei | Yang, Da | Yang, Liming | Brockway-Lunardi, Laura | Yang, Lixing | Zack, Travis I | Zenklusen, Jean C | Zhang, Hailei | Zhang, Jianhua | Zhang, Wei | Zhao, Xiaobei | Zhu, Jingchun | Zhu, Kelsey | Zimmer, Lisa | Brooks, Denise | Zmuda, Erik | Zou, Lihua | Brzezinski, Jakub | Bshara, Wiam | Buda, Elizabeth | Burns, William R | Ally, Adrian | Butterfield, Yaron S. N | Button, Michael | Calderone, Tiffany | Cappellini, Giancarlo Antonini | Carter, Candace | Carter, Scott L | Cherney, Lynn | Cherniack, Andrew D | Chevalier, Aaron | Chin, Lynda | Amin, Samirkumar B | Cho, Juok | Cho, Raymond J | Choi, Yoon-La | Chu, Andy | Chudamani, Sudha | Cibulskis, Kristian | Ciriello, Giovanni | Clarke, Amanda | Coons, Stephen | Cope, Leslie | Arachchi, Harindra | Crain, Daniel | Curley, Erin | Danilova, Ludmila | D'Atri, Stefania | Davidsen, Tanja | Davies, Michael A | Delman, Keith A | Demchok, John A | Deng, Qixia A | Deribe, Yonathan Lissanu | Arora, Arshi | Dhalla, Noreen | Dhir, Rajiv | DiCara, Daniel | Dinikin, Michael | Dubina, Michael | Ebrom, J. Stephen | Egea, Sophie | Eley, Greg | Engel, Jay | Eschbacher, Jennifer M | Auman, J. Todd | Fedosenko, Konstantin V | Felau, Ina | Fennell, Timothy | Ferguson, Martin L | Fisher, Sheila | Flaherty, Keith T | Frazer, Scott | Frick, Jessica | Fulidou, Victoria | Gabriel, Stacey B | Ayala, Brenda | Gao, Jianjiong | Gardner, Johanna | Garraway, Levi A | Gastier-Foster, Julie M | Gaudioso, Carmelo | Gehlenborg, Nils | Genovese, Gianicola | Gerken, Mark | Gershenwald, Jeffrey E | Getz, Gad
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1062489
Description: We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients. We establish a framew ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: conference paper abstract
Identifier: http://hdl.handle.net/1959.14/1060785
Description: Purpose: To evaluate the association between the immunoreactivity of the immune inhibitory ligand PD-L1 with tumour infiltrating lymphocytes (TILs) and known mechanisms of MAPK inhibitor (MAPKi) resis ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.14/1057803
Description: Purpose: To evaluate the expression of tumor PD-L1 and changes in tumor-infiltrating lymphocyte (TIL) populations in patients with metastatic melanoma treated with targeted MAPK inhibitors. Experiment ... More
Reviewed: Reviewed