Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/45503
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- Title
- Antibacterial activity in the sea urchin, Heliocidaris erythrogramma
- Related
- Lorne Conference on Protein Structure and Function (31st : 2006) (5 - 9 February 2006 : Lorne, Vic.)
- Related
- 31st Lorne proteins conference, 2006, p.68
- Publisher
- Parkville, Vic : Lorne Proteins Organising Committee
- Date
- 2006
- FoR/RFCD Code(s)
-
060705 Plant Physiology
- Author/Creator
- Wilson, G. S
- Author/Creator
- Raftos, D. A
- Author/Creator
- Nair, S. V
- Author/Creator
- Roberts, T
- Description
- The sea urchin, Heliocidaris erythrogramma, has potent antibacterial activity in its coelomic fluid. Antibacterial activity was detected by a colorimetric bactericidal assay, which revealed a minimum inhibitory concentration of 680 ppm coelomic fluid v/v in FSW. The antibacterial activity of a number of molecules was induced by bacterial challenge with maximal antibacterial activity occurring after 12 h. The molecules responsible for antibacterial activity were heat-stable and also induced by non-specific challenge. Polar extracts of coelomic fluid indicated that at least one of the factors contributing to antibacterial activity was proteinaceous. The antimicrobial peptide was approximately 13 9 kDa as determined by SDS-PAGE. The amino acid sequence and potency of the antimicrobial peptide is also discussed.
- Description
- 1 page(s)
- Subject Keyword
- 060705 Plant Physiology
- Resource Type
- conference paper abstract
- Organisation
- Macquarie University. Dept. of Chemistry and Biomolecular Sciences
- Organisation
- Macquarie University. Dept. of Biological Sciences
- Identifier
- http://hdl.handle.net/1959.14/45503
- Identifier
- ISBN:9781604237504
- Identifier
- ISSN:1034-3180
- Identifier
- mq-rm-2006000592
- Language
- eng
