Recent geochronological studies in southern Siberia support a Siberian assembly between 2.1 and 1.8 Ga. This broadly coincides with major orogenic events in most other Precambrian continents including Laurentia. In the Mesoproterozoic, Siberia was mainly an area of stable platform sedimentation whereas Laurentia underwent a continental growth from southeast. Lack of traces of the Grenville orogeny in Siberia suggests its peripheral position in Rodinia. The eastern (Uchur–Maya area) and western (Yenisei area) Siberian margins probably faced oceans during the Meso- and Neoproterozoic. Recent geological, geochronological, geochemical, and paleomagnetic data suggest integrity of Siberia and Laurentia in the Meso- and early Neoproterozoic with the Siberian southern margin close to the northern margin of Laurentia. However, some ‘intervening’ continental blocks were probably located between these two cratons. The 750–720 Ma igneous event was probably related to the rifting between Siberia and Laurentia and the opening of the Paleo-Asian Ocean, causing the development of a passive margin sedimentary succession in southern Siberia.