Entrepreneurs often face challenges and conflicts with respect to values and ethics in decision making. This mixed methods study explores a significant gap in the literature on that subject, namely the influence of self-regulation. I use survey instruments to measure two existing self-regulatory constructs termed regulatory pride and self-efficacy. The results suggest that entrepreneurs are both distinctive and heterogeneous in terms of these self-regulatory characteristics. When combined with interview data regarding their decision making behaviors, the results suggest that entrepreneurs with strong self-regulatory characteristics routinely consider values and ethics in decision making, whereas those with weak self-regulatory characteristics rarely do so.