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A Reproduction of inflow restriction in the mock circulatory system to evaluate a hydrodynamic performance of a ventricular assist device in practical conditions

Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/181762

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Title: A Reproduction of inflow restriction in the mock circulatory system to evaluate a hydrodynamic performance of a ventricular assist device in practical conditions
Related: International Conference on Life System Modeling and Simulation (2007) (14 - 17 September 2007 : Shanghai, China)
Related: Life system modeling and simulation : international conference, LSMS 2007, Shanghai, China, September 14-17, 2007 : proceedings, Vol. 4689, p.553-558
DOI: 10.1007/978-3-540-74771-0_63
Related: Lecture notes in computer science
Publisher: Berlin ; New York : Springer
Date: 2007
Author/Creator: Furusato, Masateru
Author/Creator: Shima, Tomohiro
Author/Creator: Kokuzawa, Yuma
Author/Creator: Ito, Kazuhiko
Author/Creator: Tanaka, Takashi
Author/Creator: Iwasaki, Kiyotaka
Author/Creator: Qian, Yi
Author/Creator: Umezu, Mitsuo
Author/Creator: Yan, ZhiKun
Author/Creator: Zhu, Ling
Description: A novel in vitro mock circulatory system, which enables to reproduce an inflow restriction, simulating blood volume pooling due to heart failure, was developed to evaluate a hydrodynamic performance of a pulsatile ventricular assist device (VAD) in practical conditions. The concept of this development was motivated by a difference of an inflow restriction between in vitro and in vivo environments. The major idea of this study is to reproduce an inflow restriction by using a centrifugal pump placed at an inflow side of a left ventricular model instead of a constant head reservoir in a conventional circuit. In the novel circuit, the maximum flow rate was obtained at lower systolic fraction as compared with a conventional circuit. This similar tendency by the novel one was observed in an acute animal experiment in sheep. This result suggests that a new mock circuit is effective to confirm a practical drive strategy of the VAD for various diseased conditions.
Description: 6 page(s)
Resource Type: conference paper
Organisation: Macquarie University. Australian School of Advanced Medicine

Identifier: http://hdl.handle.net/1959.14/181762
Identifier: ISBN:9783540747703
Identifier: mq-rm-2009008418
Language: eng
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