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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/181762
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- Title
- A Reproduction of inflow restriction in the mock circulatory system to evaluate a hydrodynamic performance of a ventricular assist device in practical conditions
- Related
- International Conference on Life System Modeling and Simulation (2007) (14 - 17 September 2007 : Shanghai, China)
- Related
- Life system modeling and simulation : international conference, LSMS 2007, Shanghai, China, September 14-17, 2007 : proceedings, Vol. 4689, p.553-558
- DOI
- 10.1007/978-3-540-74771-0_63
- Related
- Lecture notes in computer science
- Publisher
- Berlin ; New York : Springer
- Date
- 2007
- Author/Creator
- Furusato, Masateru
- Author/Creator
- Shima, Tomohiro
- Author/Creator
- Kokuzawa, Yuma
- Author/Creator
- Ito, Kazuhiko
- Author/Creator
- Tanaka, Takashi
- Author/Creator
- Iwasaki, Kiyotaka
- Author/Creator
- Qian, Yi
- Author/Creator
- Umezu, Mitsuo
- Author/Creator
- Yan, ZhiKun
- Author/Creator
- Zhu, Ling
- Description
- A novel in vitro mock circulatory system, which enables to reproduce an inflow restriction, simulating blood volume pooling due to heart failure, was developed to evaluate a hydrodynamic performance of a pulsatile ventricular assist device (VAD) in practical conditions. The concept of this development was motivated by a difference of an inflow restriction between in vitro and in vivo environments. The major idea of this study is to reproduce an inflow restriction by using a centrifugal pump placed at an inflow side of a left ventricular model instead of a constant head reservoir in a conventional circuit. In the novel circuit, the maximum flow rate was obtained at lower systolic fraction as compared with a conventional circuit. This similar tendency by the novel one was observed in an acute animal experiment in sheep. This result suggests that a new mock circuit is effective to confirm a practical drive strategy of the VAD for various diseased conditions.
- Description
- 6 page(s)
- Resource Type
- conference paper
- Organisation
- Macquarie University. Australian School of Advanced Medicine
- Identifier
- http://hdl.handle.net/1959.14/181762
- Identifier
- ISBN:9783540747703
- Identifier
- mq-rm-2009008418
- Language
- eng
- Reviewed
Macquarie University ResearchOnline
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