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-List Of Titles -Midterm outcomes of paclitaxel-eluting stents for the treatment of intracranial posterior circulation stenoses

Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/180429

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Title
Midterm outcomes of paclitaxel-eluting stents for the treatment of intracranial posterior circulation stenoses
Related
Journal of neurosurgery, Vol. 106, Issue 2, (2007), p.222-225
DOI
10.3171/jns.2007.106.2.222
Publisher
American Association of Neurosurgeons
Date
2007
FoR/RFCD Code(s)
110900 Neurosciences  110300 Clinical Sciences
Author/Creator
Steinfort, Brendan
Author/Creator
Ng, Perry P
Author/Creator
Faulder, Kenneth
Author/Creator
Harrington, Timothy
Author/Creator
Grinnell, Verity
Author/Creator
Sorby, William
Author/Creator
Morgan, Michael K
Description
OBJECT: Symptomatic intracranial vertebral and basilar artery atherosclerotic stenoses carry a high risk of stroke and permanent disability if refractory to maximal medical therapy. The authors conducted a study to determine the technical feasibility and midterm clinical and angiographic outcomes in patients in whom paclitaxel-eluting stents were placed for the treatment of symptomatic intracranial posterior circulation stenoses. METHODS: A retrospective review of medical records and imaging studies was performed for 13 consecutive patients in whom paclitaxel-coated stents were used to treat symptomatic posterior circulation intracranial stenoses between 2002 and 2005. Clinical follow-up data were supplemented by telephone interviews. The technical success rate for stent placement was 100%. One patient (8%) suffered a periprocedural stroke. Twelve patients (92%) underwent clinical follow up for a minimum of 3 months postsurgery, and 11 (92%) of these patients remained asymptomatic after a mean period of 10.9 months. Nine patients (69%) underwent catheter angiographic follow up, and no patient had significant in-stent recurrence of stenosis after a mean period of 5.4 months. CONCLUSIONS: Treatment of intracranial posterior circulation stenoses with drug-eluting stents is technically feasible, and the rate of clinically significant periprocedural complications is low. Rates of stenosis recurrence are reduced compared with those of bare-metal stents in the midterm. Midterm clinical outcome is excellent; no symptom recurrence was observed in this patient cohort.
Description
4 page(s)
Subject Keyword
110900 Neurosciences
Subject Keyword
110300 Clinical Sciences
Subject Keyword
intracranial stenosis
Subject Keyword
vertebrobasilar artery
Subject Keyword
stent
Subject Keyword
angioplasty
Resource Type
journal article
Organisation
Macquarie University. Australian School of Advanced Medicine

Identifier
http://hdl.handle.net/1959.14/180429
Identifier
ISSN:0022-3085
Identifier
mq-rm-2007009731
Language
eng
Reviewed
Reviewed
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Citation Format
E-mail Address
Subject
"Journal of neurosurgery"
 
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