Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/180429
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- Title
- Midterm outcomes of paclitaxel-eluting stents for the treatment of intracranial posterior circulation stenoses
- Related
- Journal of neurosurgery, Vol. 106, Issue 2, (2007), p.222-225
- DOI
- 10.3171/jns.2007.106.2.222
- Publisher
- American Association of Neurosurgeons
- Date
- 2007
- FoR/RFCD Code(s)
-
110900 Neurosciences
110300 Clinical Sciences
- Author/Creator
- Steinfort, Brendan
- Author/Creator
- Ng, Perry P
- Author/Creator
- Faulder, Kenneth
- Author/Creator
- Harrington, Timothy
- Author/Creator
- Grinnell, Verity
- Author/Creator
- Sorby, William
- Author/Creator
- Morgan, Michael K
- Description
- OBJECT: Symptomatic intracranial vertebral and basilar artery atherosclerotic stenoses carry a high risk of stroke and permanent disability if refractory to maximal medical therapy. The authors conducted a study to determine the technical feasibility and midterm clinical and angiographic outcomes in patients in whom paclitaxel-eluting stents were placed for the treatment of symptomatic intracranial posterior circulation stenoses. METHODS: A retrospective review of medical records and imaging studies was performed for 13 consecutive patients in whom paclitaxel-coated stents were used to treat symptomatic posterior circulation intracranial stenoses between 2002 and 2005. Clinical follow-up data were supplemented by telephone interviews. The technical success rate for stent placement was 100%. One patient (8%) suffered a periprocedural stroke. Twelve patients (92%) underwent clinical follow up for a minimum of 3 months postsurgery, and 11 (92%) of these patients remained asymptomatic after a mean period of 10.9 months. Nine patients (69%) underwent catheter angiographic follow up, and no patient had significant in-stent recurrence of stenosis after a mean period of 5.4 months. CONCLUSIONS: Treatment of intracranial posterior circulation stenoses with drug-eluting stents is technically feasible, and the rate of clinically significant periprocedural complications is low. Rates of stenosis recurrence are reduced compared with those of bare-metal stents in the midterm. Midterm clinical outcome is excellent; no symptom recurrence was observed in this patient cohort.
- Description
- 4 page(s)
- Subject Keyword
- 110900 Neurosciences
- Subject Keyword
- 110300 Clinical Sciences
- Subject Keyword
- intracranial stenosis
- Subject Keyword
- vertebrobasilar artery
- Subject Keyword
- stent
- Subject Keyword
- angioplasty
- Resource Type
- journal article
- Organisation
- Macquarie University. Australian School of Advanced Medicine
- Identifier
- http://hdl.handle.net/1959.14/180429
- Identifier
- ISSN:0022-3085
- Identifier
- mq-rm-2007009731
- Language
- eng
- Reviewed
