pJIE137 carrying blaCTX-M-62 is closely related to p271A carrying blaNDM-1 | Macquarie University ResearchOnline

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Title: pJIE137 carrying blaCTX-M-62 is closely related to p271A carrying blaNDM-1
Related: Antimicrobial agents and chemotherapy, Vol. 56, No. 4, (2012), p.2166-2168
DOI: 10.1128/AAC.05796-11
Publisher: American Society for Microbiology
Date: 2012
Author/Creator: Partridge, Sally R
Author/Creator: Paulsen, Ian T
Author/Creator: Iredell, Jonathan R
Description: Complete sequencing of pJIE137 revealed a backbone closely related to p271A, encoding a novel RepA protein but with a similar organization and up to ∼70% nucleotide identity to IncN plasmids. A region in pJIE137 resembling the IncN CUP regulon is mostly missing from p271A, presumably due to recombination. The class 1 In/Tn and ISEcp1-bla CTX-M-62 transposition unit in pJIE137 and a putative transposon carrying bla NDM-1 in p271A are inserted in different locations in the plasmid backbone.
Description: 3 page(s)
Resource Type: journal article
Organisation: Macquarie University. Dept. of Chemistry and Biomolecular Sciences

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