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Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/152412
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- Title
- The Effect of delineation method and observer variability on bladder dose-volume histograms for prostate intensity modulated radiotherapy
- Related
- Radiotherapy and oncology, Vol. 101, Issue 3, (2011), p.479-485
- DOI
- 10.1016/j.radonc.2011.06.039
- Publisher
- Elsevier
- Date
- 2011
- Author/Creator
- Rosewall, Tara
- Author/Creator
- Bayley, Andrew J
- Author/Creator
- Chung, Peter
- Author/Creator
- Le, Lisa W
- Author/Creator
- Xie, Jason
- Author/Creator
- Baxi, Siddhartha
- Author/Creator
- Catton, Charles N
- Author/Creator
- Currie, Geoffrey M
- Author/Creator
- Wheat, Janelle M
- Author/Creator
- Milosevic, Michael
- Description
- Purpose: To quantify the effect of delineation method on bladder DVH, observer variability (OV) and contouring time for prostate IMRT plans. Materials and methods: Planning CT scans and IMRT plans of 30 prostate cancer patients were anonymized. For 20 patients, 1 observer delineated the bladder using 9 methods. The effect of delineation method on the DVH curve, discrete dose levels and delineation time was quantified. For the 10 remaining CTs, 6 observers delineated bladder wall using 4 methods. Observer-based volume variation and intraclass correlation coefficient (ICC) were used to describe the dosimetric effects of OV. Results: Manual delineation of the bladder wall (BW-m) was significantly slower than any other method (mean: 20 min vs. ≤13 min) and the dosimetric effect of OV was significantly larger (V70 Gy ICC: 0.78 vs. 0.98). Only volumes created using a 2.5 mm contraction from the outer surface, and a method providing a consistent wall volume, showed no notable dosimetric differences from BW-m in both absolute and relative volume. Conclusions: Automatic contractions from the outer surface provide quicker, more reproducible and reasonably accurate substitutes for BW-m. The widespread use of automatic contractions to create a bladder wall volume would assist in the consistent application of IMRT dose constraints and the interpretation of reported dose.
- Description
- 7 page(s)
- Subject Keyword
- 111200 Oncology and Carcinogenesis
- Subject Keyword
- External beam
- Subject Keyword
- IMRT
- Subject Keyword
- Normal tissue
- Subject Keyword
- Observer error
- Subject Keyword
- Organ at risk
- Subject Keyword
- Organ definition
- Resource Type
- journal article
- Organisation
- Macquarie University. Australian School of Advanced Medicine
- Identifier
- http://hdl.handle.net/1959.14/152412
- Identifier
- mq:17043
- Identifier
- ISSN:0167-8140
- Identifier
- mq-rm-2011003905
- Identifier
- mq_res-ext-2-s2.0-81855218606
- Language
- eng
- Reviewed
Macquarie University ResearchOnline
