Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/144455
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- Title
- Synthesis and reactivity of dimethoxy-functionalised Tröger's base analogues
- Related
- Tetrahedron, Vol. 67, No. 32, (2011), p.5798-5805
- DOI
- 10.1016/j.tet.2011.05.128
- Publisher
- Elsevier
- Date
- 2011
- Author/Creator
- Malik, Qasim M
- Author/Creator
- Ijaz, Sadia
- Author/Creator
- Craig, Donald C
- Author/Creator
- Try, Andrew C
- Description
- Tröger's base analogues were prepared bearing methoxy groups in the 1,7-, 2,8-, 3,9- or 4,10-positions. These compounds were converted to their dihydroxy analogues in excellent yields upon treatment with boron tribromide and the 4,10-dihydroxy analogue could be prepared by directly from 4-hydroxyaniline. The synthetic utility of the dihydroxy-functionalised compounds as building blocks was demonstrated by the synthesis of a dialkoxy and a diester Tröger's base analogue.
- Description
- 8 page(s)
- Subject Keyword
- Aromatic Amines
- Subject Keyword
- Chirality
- Subject Keyword
- Demethylation
- Subject Keyword
- Tröger's base
- Resource Type
- journal article
- Organisation
- Macquarie University. Dept. of Chemistry and Biomolecular Sciences
- Identifier
- http://hdl.handle.net/1959.14/144455
- Identifier
- ISSN:0040-4020
- Identifier
- mq_res-ext-2-s2.0-79960033792
- Language
- eng
- Reviewed
