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Title: Critical particle size for fractionation by deterministic lateral
Related: Lab on a chip, Vol. 6, Issue 5 (2006), p.655-658
DOI: 10.1039/B515371A
Publisher: Royal Society of Chemistry
Date: 2006
FoR/RFCD Code(s): 091500 Interdisciplinary Engineering
Author/Creator: Inglis, David W
Author/Creator: Davis, John A
Author/Creator: Austin, Robert H
Author/Creator: Sturm, James C
Description: The fractionation of small particles in a liquid based on their size in a micropost array by deterministic lateral displacement was recently demonstrated with unprecedented resolution (L. R. Huang, E. C. Cox, R. H. Austin and J. C. Sturm, Science, 2004, 304, 987–990, ref. 1). In this paper, we present a model of how the critical particle size for fractionation depends on the micropost geometry, depending specifically on the gap between posts, the offset of posts in one row with respect to another, and whether the fluid is driven by hydrodynamics or by electroosmosis. In general the critical particle diameter is much smaller than the gap, which prevents clogging. The model is supported by data with particles from 2.3 to 22 μm.
Description: 4 page(s)
Subject Keyword: 091500 Interdisciplinary Engineering
Resource Type: journal article
Organisation: Macquarie University. Dept. of Physics and Astronomy

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