Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/114440
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- Title
- Synthesis and design of bifunctional phosphine catalysts for the asymmetric Morita Baylis Hillman reaction (MBH)
- Related
- New Zealand Institute of Chemistry Conference (2 - 6 December 2006 : Rotorua, New Zealand)
- Related
- Lein, Matthias. Proceedings of the NZIC 2006 : back to the basics : from small molecules to materials and surfaces, Vol. II, posters, p.86-87
- Related
- http://www.massey.ac.nz/~nzic/BookOfAbstracts-Part-2.pdf
- Publisher
- Rotorua, New Zealand : The New Zealand Institute of Chemistry
- Date
- 2006
- FoR/RFCD Code(s)
-
030503 Organic Chemical Synthesis
- Author/Creator
- Smith, Karen Patricia
- Author/Creator
- Liu, Fei
- Description
- MBH is an atom efficient reaction that provides densely functionalised adducts and generates a chiral centre [1,2]. The reaction can be extremely slow and is highly substrate dependant. An appropriately positioned protic functional group within the catalyst is essential for enantioselectivity. Our aim is to establish the catalytic activity of a series of chiral [2’-diphenylphosphinoyl-[1,1]-binaphthyl] amine derivatives for the Morita-Baylis-Hillman reaction. Two synthetic approaches will be evaluated starting with 2,2’dibromo-1,1-binaphthyl; amine functionality will be introduced either through a Buchwald-Harwig [4] strategy or an intermolecular Staudinger [5] reaction.
- Description
- 2 page(s)
- Subject Keyword
- 030503 Organic Chemical Synthesis
- Resource Type
- conference poster
- Organisation
- Macquarie University. Dept. of Chemistry and Biomolecular Sciences
- Identifier
- http://hdl.handle.net/1959.14/114440
- Identifier
- ISBN:9780473118549
- Identifier
- mq-rm-2006007735
- Language
- eng
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