Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.14/114171
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- Title
- Characterisation of the CD5 cDNA sequence from the tammar wallaby (Macropus eugenii)
- Related
- Veterinary immunology and immunopathology, Vol. 131, No. 1-2 (2009), p.117-121
- DOI
- 10.1016/j.vetimm.2009.03.005
- Publisher
- Elsevier
- Date
- 2009
- FoR/RFCD Code(s)
-
060800 Zoology
070400 Fisheries Sciences
070700 Veterinary Sciences
- Author/Creator
- Duncan, L. G
- Author/Creator
- Old, J. M
- Description
- CD5 has previously been identified in marsupial tissues using anti-human CD5. However, despite the known cross-reactivity of the antibody in marsupial tissues, the cDNA sequence has not previously been characterised in any marsupial. This study has identified the CD5 gene in the opossum genome database and has characterised the CD5 cDNA sequence from the tammar wallaby. Both marsupial CD5 sequences have a high level of sequence identity to known eutherian CD5 sequences, are cysteine-rich and have identical structural motifs to their eutherian homologs. CD5 transcripts were strongly expressed in adult tammar wallaby spleen, mammary node and blood, and expressed at a lower level in liver, kidney and heart tissues. Characterisation of CD5 in marsupials allowed a comparison to the epitope sequence of anti-human CD5 and showed a high level of sequence identity.
- Description
- 5 page(s)
- Subject Keyword
- 060800 Zoology
- Subject Keyword
- 070400 Fisheries Sciences
- Subject Keyword
- 070700 Veterinary Sciences
- Subject Keyword
- marsupial
- Subject Keyword
- macropod
- Subject Keyword
- tammar wallaby
- Subject Keyword
- CD5
- Subject Keyword
- opossum
- Resource Type
- journal article
- Organisation
- Macquarie University. Dept. of Biological Sciences
- Identifier
- http://hdl.handle.net/1959.14/114171
- Identifier
- ISSN:0165-2427
- Identifier
- mq-rm-2009002847
- Language
- eng
- Reviewed
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