A novel reduction reaction for the conversion of aldehydes, ketones and primary, secondary and tertiary alcohols into their corresponding alkanes | Macquarie University ResearchOnline

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Title: A novel reduction reaction for the conversion of aldehydes, ketones and primary, secondary and tertiary alcohols into their corresponding alkanes
Related: Tetrahedron letters, Vol. 47, Issue 32, p.5755-5758
DOI: 10.1016/j.tetlet.2006.06.007
Publisher: Elsevier Science
Date: 2006
Author/Creator: Nimmagadda, Rama D
Author/Creator: McRae, Christopher
Description: A novel one-pot reaction has been developed for the reduction of aldehydes, ketones and primary, secondary and tertiary alcohols into their corresponding alkyl function. This is also the first reported method which can efficiently reduce primary, secondary, or tertiary alcohols, without affecting carbon–carbon double bonds, into their corresponding alkyl function in high yields. The reduction utilises either diethylsilane or n-butylsilane as the reducing agent in the presence of the Lewis acid catalyst tris(pentafluorophenyl)borane.
Description: 4 page(s)
Subject Keyword: reduction
Subject Keyword: aldehydes
Subject Keyword: ketones
Subject Keyword: alcohols
Subject Keyword: DES : diethylsilane
Subject Keyword: n-BS : n-butylsilane
Subject Keyword: B(C₆F₅)₃ : tris(pentafluorophenyl)borane
Resource Type: journal article
Organisation: Macquarie University. Dept. of Chemistry and Biomolecular Sciences

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